| 李 军,何永明,江海东.四川盐亭与河北磁县1988~2007年贲门癌发病趋势分析[J].中国肿瘤,2013,22(5):344-349. |
| 四川盐亭与河北磁县1988~2007年贲门癌发病趋势分析 |
| Incidence Trends of Gastric Cardia Carcinoma in Yanting County and Cixian County，1988~2007 |
| 投稿时间：2012-12-04 |
| DOI：10.11735/j.issn.1004-0242.2013.05.2012352 |
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| 中文关键词: 贲门癌 发病 年度变化百分比 食管癌高发区 |
| 英文关键词:gastric cardia carcinoma incidence annual percentage change high risk areas of esophageal cancer |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 根据四川盐亭和河北磁县肿瘤登记处数据，比较1988~2007年中国两个不同地域食管癌高发区贲门癌发病趋势的变化。［方法］ 截取1988~2007年发病数据库ICD编码C16.0，组织学诊断比例76.4%～78.8％。贲门癌的发病采用y=α＋βx+ε线性模型，计算年度变化百分比（APC）。［结果］ 四川盐亭1988年贲门癌中标率为11.04/10万，2007年17.66/10万；河北磁县则分别为7.62/10万和37.41/10万。四川盐亭贲门癌发病呈明显上升，男女合计贲门癌发病APC 为5.89%，其中男性２.８７%，女性２.８４％，有统计学差异;河北磁县贲门癌发病的APC分别为7.66%、8.13%和6.46%（P=0.000）。［结论］ 中国两个不同地域食管癌高发区人群20年贲门癌发病均呈现明显的增长趋势，发病显著增高的原因与ICD编码规则和内镜的临床广泛应用关系密切。 |
| 英文摘要: |
| Abstract: ［Purpose］ To compare incidence trends of gastric cardia carcinoma in two high risk areas of esophageal cancer from 1988 to 2007. ［Methods］ Extracting disease code of ICD C16.0 from 1988~2007 cancer database，the morphology verified cases accounted for 76.4%～78.8%. Incidence of gastric cardia carcinoma used linear model of y=α＋βx+ε to calculate annual percentage change (APC). ［Results］ The age-standardized incidence rates of gastric cardia carcinoma by China population in Yanting were 11.04/105 in 1988 and 17.66/105 in 2007; in Cixian the rates were 7.62/105 and 37.41/105 respectively. In Yanting，the incidence of gastric cardia carcinoma had an increasing trend，and the APC was 5.89% (2.87% for male and 2.84% for female). In Cixian，the APC was 7.66% (8.13% for male and 6.46% for female). ［Conclusion］ The incidences of gastric cardia carcinoma have obvious increasing trends both in Yanting and Cixian. It might correlate with coding rule of ICD and widespread using of endoscope. |
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