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| 热消融在肝细胞癌中的应用及进展 |
| Applications and Advances of Thermal Ablation in Hepatocellular Carcinoma |
| 投稿时间：2025-01-06 修订日期：2025-05-27 |
| DOI： |
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| 中文关键词: 肝细胞癌 热消融 完全消融 联合治疗 综述 |
| 英文关键词:Hepatocellular carcinoma Thermal ablation Complete ablation Combined Therapy Review |
| 基金项目:国家自然科学基金项目（面上项目，重点项目，重大项目）,山东省自然科学基金项目 |
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| 中文摘要: |
| 肝癌是全球第六大常见恶性肿瘤，同时也是癌症相关性死亡的第三大原因。其中，肝细胞癌（Hepatocellular Carcinoma,HCC）是最常见的类型，约占所有原发性肝癌的90％。早期治疗对肝细胞癌患者的预后至关重要，热消融作为一种微创治疗手段，对肝功能影响小、创伤小，是不适合手术切除治疗的早期患者的一线治疗选择。近年来，热消融在临床中的应用逐渐增多。然而，据相关报道，热消融后肝细胞癌的5年内复发率可达50％-70％，这主要是因为消融不完全，因此实现完全消融对于提高肝细胞癌患者的预后至关重要。本文综述了热消融在肝细胞癌治疗中的应用进展，并探讨了实现完全消融的方法。 |
| 英文摘要: |
| Hepatocellular carcinoma (HCC) is the sixth most common malignant tumor worldwide and the third leading cause of cancer-related death. HCC is the most prevalent type of primary liver cancer, accounting for approximately 90% of cases. Early treatment is crucial for improving prognosis in liver cancer patients. Thermal ablation, as a minimally invasive treatment method, has minimal impact on liver function and causes less trauma, making it a first-line treatment choice for early-stage patients who are not suitable for surgical resection. In recent years, the clinical application of Thermal Ablation has been increasing. However, reports indicate that the 5-year recurrence rate of HCC after thermal ablation can reach 50％-70%, primarily due to incomplete ablation. Therefore, achieving complete ablation is essential for improving the prognosis of HCC patients. This review summarizes the progress in the application of thermal ablation techniques in liver cancer treatment and explores methods for achieving complete ablation. |
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