| [Purpose] To analyze the epidemiological characteristics of corpus uteri cancer in Zhejiang Province in 2021 and its incidence and mortality trends from 2000 to 2021, providing evidence for establishing an effective prevention and control system. [Methods] Data on corpus uteri cancer incidence and mortality (2000~2021) from 22 cancer registries in Zhejiang Province were collected. SAS9.4 and Joinpoint 5.3.0 were used to calculate crude rates, age-standardized rates (ASR), truncated rates, cumulative rates, age-specific rates, and average annual percentage changes (AAPC) for both incidence and mortality. [Results] In 2021, the crude incidence rate of corpus uteri cancer was 12.15/105(peak in 55–59 age group), with ASRC and ASRW of 6.99/105and 6.80/105, ranking 10th among female cancers. The crude mortality rate was 1.85/105?(peak in ≥85 age group), with ASRC and ASRW of 0.88/105and 0.86/105, ranking 14th in female cancer deaths. From 2000 to 2021, the crude incidence increased significantly (AAPC=3.88%,?95%CI=2.94%~5.00%,P<0.05), though the standardized incidence growth rate moderated (AAPC for ASRC and ASRW incidence rates were 2.15% and 2.21%, respectively, both?P<0.05), with statistical significance (P<0.05). The crude mortality rate exhibited no significant change (AAPC=-0.78%, 95%CI=-2.25%~1.69%,P>0.05), but standardized mortality rates declined significantly (AAPC for ASRC and ASRW mortality rates were -2.77% and -2.75%, respectively, both P<0.05), demonstrating statistical significance (P<0.05). [Conclusion] The incidence of corpus uteri cancer in Zhejiang shows a fluctuating upward trend, with higher risk in middle-aged women, while mortality exhibits a declining trend, with higher risk in elderly women and notable urban-rural disparities. Strengthened health education, promotion of healthy lifestyles, early detection, diagnosis, and treatment, along with efforts to reduce urban-rural gaps and improve primary healthcare equity, are recommended. |
