Cancer incidence in China has been rising steadily, with a particularly heavy burden from several high-prevalence malignancies. Medical examination for cancer plays a critical role in the early detection of cancer, precancerous lesions, and precursor conditions, thereby facilitating timely diagnosis and intervention. Such examination also addresses the growing demand for personalized cancer screening services among diverse population groups. The development of evidence-based, context-specific cancer screening guidelines is essential to enhance the standardization, quality, and equity of preventive screening practices across the country, ultimately improving outcomes in early cancer detection and treatment. Guided by the Department of Medical Emergency Response of the National Health Commission, the Guidelines for medical examination for cancer in Health Examination Agency (2025 Edition) were developed under the leadership of the National Cancer Center. A multidisciplinary panel of experts formulated the guidelines in accordance with the principles and methodology of the World Health Organization Handbook for Guideline Development. The guidelines provide evidence-based recommendations on eight key clinical domains: target cancers and populations, overall screening workflow, screening protocols, diagnostic technologies, result interpretation, follow-up procedures, and quality control. The primary objective is to standardize cancer screening practices in health examination agency and strengthen China’s capacity for prevention and control of high-burden cancers. |