| 中文关键词: 肿瘤 癌性贫血 危险因素 |
| 英文关键词:neoplasm cancer-related anemia risk factor |
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| 中文摘要: |
| 摘 要:［目的］ 探讨恶性肿瘤患者贫血的发生情况及其相关危险因素。［方法］ 回顾性分析我院综合科2010年1月至12月收治的986例恶性肿瘤患者，进行单因素和多因素Logistic回归分析。［结果］ 所有患者中，男性573例（58.2%），女性413例（41.8%），死亡124例，贫血669例，贫血发生率为67.8%。Ⅰ级295例（44.1%)，Ⅱ级218例(32.6%)，Ⅲ级87例(13.0%)，Ⅳ级69例(10.3%)。胃肠道肿瘤贫血发生率最高为77.5％。单因素分析显示，年龄、肿瘤分期、抗肿瘤治疗、肿瘤类型、合并出血与恶性肿瘤贫血的发生有关，具有统计学意义（P<0.05）。多因素Logistic回归分析显示，合并出血、临床分期、抗肿瘤治疗与贫血发生密切相关。［结论］ 恶性肿瘤患者贫血发生率较高；肿瘤分期、合并出血和抗肿瘤治疗是恶性肿瘤贫血发生的危险因素。 |
| 英文摘要: |
| Abstract:［Purpose］ To explore the occurrence of anemia in patients with malignancy and the related risk factors.［Methods］ A retrospective analysis was performed in 986 patients with malignancy from January to December (2010) by single factor analysis and multivarite logistic analysis. ［Results］ Among all the cases，there were 573（58.2%） in male，413（41.8%） in female and 124 patients died of cancer. Anemia occurred in 669 cases account for 67.8% of all the cases with malignancy. Based on anemia grading，295 cases(44.1%) was grade Ⅰ，218(32.6%) grade Ⅱ，87(13.0%) grade Ⅲ，69 (10.3%) grade Ⅳ. Gastrointestinal cancer was the highest occurence of anemia with 77.5%.Univariant analysis demonstrated that anemia was correlated to age，grade，anti-neoplastic therapy，tumor type and combined bleeding，with statistic significance(P<0.05). Multivarite logistic analysis showed that bleeding，and anti-neoplastic therapy were significantly correlated to anemia.［Conclusion］ Patients with malignancy have a high occurence of anemia. Tumor stage，bleeding and anti-neoplastic therapy are the risk factors of anemia in patients with malignancy. |
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