| 魏葆珺,李学祥,齐 军.防癌筛查妇女中人乳头状瘤病毒感染状况分析[J].中国肿瘤,2013,22(11):885-887. |
| 防癌筛查妇女中人乳头状瘤病毒感染状况分析 |
| An Analysis on HPV Infection Status in Screened Women |
| 投稿时间：2013-03-13 |
| DOI：10.11735/j.issn.1004-0242.2013.11.A008 |
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| 中文关键词: 人乳头状瘤病毒 导流杂交 筛查 宫颈癌 |
| 英文关键词:human papillomavirus HybriMax screening cervical cancer |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 了解防癌筛查妇女中HPV感染状况及分布特点，为宫颈癌防治提供依据。［方法］ 采用HybriMax技术对5880例防癌筛查妇女进行HPV感染检测。［结果］ 5880例防癌筛查妇女中HPV阳性1105例，阳性率为18.80%，21种型别均被检测出。高危型以HPV16、HPV52和HPV58最常见，低危型最常见的为HPV53和HPVcp8304。阳性感染者中228例为多重感染，多重感染率为3.88%（228/5880），占阳性例数的20.63%，其中二重感染最多见。［结论］ HPV亚型感染分布以HPV16、HPV52和HPV58为主，其分布与宫颈癌前病变及宫颈癌密切相关。 |
| 英文摘要: |
| Abstract:［Purpose］ To investigate the HPV infection status and age distribution in screened women，to provide basis for prevention and control of cervical cancer. ［Methods］ A total number of 5880 cases were detected for HPV by HybriMax. ［Results］ The number of positive cases was 1105 out of 5880. Positive rate of HPV infection was 18.80%. All the 21 genotypes of HPV were tested out. The most common high-risk genotype were HPV16，HPV52 and HPV58，whereas HPV16 and HPVcp8304 were the most common low-risk genotypes. The multiple infection rate was 3.88%（228/5880）. Double infection was common. ［Conclusion］ HPV16，HPV52 and HPV58 serves as the most common genotypes in HPV. The HPV distribution closely correlates to cervical precancerous lesions and cervical cancer. |
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