钟宇新,毕 超.25例腹内型侵袭性纤维瘤病临床分析[J].中国肿瘤,2013,22(12):1025-1028.
25例腹内型侵袭性纤维瘤病临床分析
Clinical Analysis of 25 Cases with Intra-abdominal Aggressive Fibromatosis
投稿时间:2013-09-30  
DOI:10.11735/j.issn.1004-0242.2013.12.A015
中文关键词:  侵袭性纤维瘤病  手术  肿瘤大小  预后
英文关键词:aggressive fibromatosis  surgery  tumor size  prognosis
基金项目:
作者单位
钟宇新 中国医学科学院肿瘤医院 
毕 超 中国医学科学院肿瘤医院 
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中文摘要:
      摘 要: [目的] 探讨腹内型侵袭性纤维瘤病的临床特点、治疗方法和预后。[方法] 回顾性分析1999年1月至2013年3月收治的25例腹内型侵袭性纤维瘤病患者的临床资料,生存分析采用Kaplan-Meier法。[结果] 5、10年生存率分别为94.4%和70.7%,无复发生存率分别为68.7%和58.9%。肿瘤最大径≥10cm(χ2=5.074,P=0.024)和接受姑息性手术(χ2=6.131,P=0.013)的患者预后较差。[结论] 腹内型侵袭性纤维瘤病术前难以确诊,首选手术治疗,肿瘤大小和能否根治性切除是其预后影响因素。
英文摘要:
      Abstract:[Purpose] To investigate the clinical characteristics,treatments and prognostic risk factors of patients with intra-abdominal aggressive fibromatosis.[Methods] The clinical data of 25 cases with intra-abdominal aggressive fibromatosis admitted from January 1999 to March 2013 were retrospectively analyzed. The survival functions were analyzed by Kaplan-Meier. [Results] The 5-year and 10-year survival was 94.4% and 70.7%,respectively. The 5-year and 10-year recurrence-free survival rate was 68.7% and 58.9%,respectively. Prognosis of patients with tumor size≥10cm(χ2=5.074,P=0.024)and undergoing palliative operation (χ2=6.131,P=0.013) was worse than that with size<10cm and undergoing radical operation. [Conclusion] It is difficult to diagnose the intra-abdominal aggressive fibromatosis before operation. Surgery is the first choice of treatment. Tumor size and weather radical surgery being performed are risk factors of the prognosis of intra-abdominal aggressive fibromatosis.
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