| 张永辉,陈建国,朱 健.启东市1972~2011年乳腺癌发病趋势分析[J].中国肿瘤,2014,23(8):636-641. |
| 启东市1972~2011年乳腺癌发病趋势分析 |
| An Analysis of Incidence Trend of Breast Cancer in Qidong，1972～2011 |
| 投稿时间：2014-04-14 |
| DOI：10.11735/j.issn.1004-0242.2014.08.A003 |
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| 中文关键词: 乳腺癌 发病率 流行病学 启东 |
| 英文关键词:breast cancer incidence epidemiology Qidong |
| 基金项目: |
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| 摘要点击次数: 2070 |
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| 中文摘要: |
| 摘 要：［目的］ 探讨启东市1972~2011年乳腺癌发病变化趋势，为乳腺癌预防控制提供依据。［方法］ 根据启东市1972~2011年癌症发病登记数据库，对乳腺癌发病率作年龄、时间趋势分析，计算指标包括粗发病率、中国人口标化率（中标率）、世界人口标化率（世标率）、35~64岁截缩率、0~74岁累积率、累积风险、变化百分比（PC）及年均变化百分比（APC）等。［结果］ 1972~2011年启东男女性乳腺癌共发病3452例，粗发病率为7.68/10万，占全部癌症发病的3.72%，位居癌症发病第6位。中标率和世标率分别为4.65/10万和6.13/10万；35~64岁截缩发病率为15.31/10万；0~74岁累积发病率为0.64%；乳腺癌发病的累积风险为0.64%。男女性乳腺癌发病性别比为1∶62.93。女性乳腺癌位居女性癌症发病的第4位，粗率、中标率和世标率分别为14.94/10万、9.00/10万和11.78/10万。女性乳腺癌的发病率随年龄的增加而升高，35~岁组进入增长期，50~岁组达到发病率高峰，为37.10/10万。40年间女性乳腺癌发病的粗率、中标率和世标率的变化百分比（PC）分别为269.74%、73.80%和81.48%，年均变化百分比（APC）分别为3.38%、1.21%和1.31%。各时期女性乳腺癌发病率显示25~34岁年龄组的升降趋势不明显，35~岁以后各年龄组的发病率均有上升趋势。年龄-出生队列方法分析女性乳腺癌，显示40~岁以后各年龄组的发病率均呈上升趋势。［结论］ 启东近40年来女性乳腺癌发病率有上升趋势，40岁以上的女性是乳腺癌防治的重点。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the incidence trend of breast cancer from 1972 to 2011 in Qidong，and to provide basis for making control measures and strategies for prevention. ［Methods］ The cancer registration data of 1972～2011 were collected and analyzed for the incidence of breast cancer by age and time trend. Crude incidence，age-standardized incidence by Chinese standard population(ASR China) and by world standard population(ASR world)，truncated rate (35～64 age years old)，cumulative rate (0～74 age years old)，cumulative risk，percentage change (PC)，annual percentage change (APC)，incidence by period and birth-cohort were calculated. ［Results］ The new breast cancer cases were 3452 cases from 1972 to 2011，accounted for 3.72% of the total cancer incidence，ranked 6th.The crude incidence，ASR China and ASR world were 7.68%/105，4.65/105 and 6.13/105，respectively. Truncated rate (35～64 age years old)，cumulative rate(0～74 age years old) and cumulative risk were 15.31/105，0.64% and 0.64%，respectively. The sex ratio of male to female was 1：62.93.The female breast cancer ranked 4th of all cancer sites in female，the crude incidence，ASR China and ASR world were 14，94/105，9.00/105 and 11.78/105. The incidence of female breast cancer increased with age，showing a rapid increase after age of 35 years，and a peek rate of 37.10/105 at age of 50～years group. During the forty years period，the PCs of crude incidence，ASR China and ASR world of female breast cancer were 269.74%，73.80% and 81.48%，and the APCs，3.38%，1.21% and 1.31%，respectively. Age-specific incidence by period showed no significant up-down trends at age of 25～34 years，but upward trends after 35 years and over. Birth-cohort analysis illustrated the rising trends in incidence for those over age of 40 years. ［Conclusion］ The incidence of female breast cancer increased from 1972 to 2011 in Qidong；the attention should be paid for women over 40 years in prevention of breast cancer. |
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