闫 炎,吴 齐,步召德.术前超声内镜对早期胃癌浸润深度的诊断价值及其影响因素分析[J].中国肿瘤,2014,23(12):1039-1043.
术前超声内镜对早期胃癌浸润深度的诊断价值及其影响因素分析
The Value of Endoscopic Ultrasound for the Diagnosis of Depth of Tumor Invasion in Early Gastric Cancer and Its Related Factors
投稿时间:2014-05-05  
DOI:10.11735/j.issn.1004-0242.2014.12.A017
中文关键词:  超声内镜  早期胃癌  黏膜下浸润
英文关键词:endoscopic ultrasound  early gastric cancer  submucosal infiltration
基金项目:
作者单位
闫 炎 北京大学肿瘤医院暨北京市肿瘤防治研究所恶性肿瘤发病机制及转化研究教育部重点实验室 
吴 齐 北京大学肿瘤医院暨北京市肿瘤防治研究所恶性肿瘤发病机制及转化研究教育部重点实验室 
步召德 北京大学肿瘤医院暨北京市肿瘤防治研究所恶性肿瘤发病机制及转化研究教育部重点实验室 
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中文摘要:
      摘 要:[目的] 探讨超声内镜对早期胃癌浸润深度诊断的准确性及影响因素分析。[方法] 回顾性分析2012~ 2013年行术前超声内镜检查且超声内镜分期为T1、术后获得明确病理诊断为早期胃癌临床病例138例,比较超声内镜与病理判断肿瘤黏膜下浸润的一致性,以及影响超声内镜分期准确性的相关因素。[结果] 在138例病例中,超声内镜诊断黏膜下层受侵与否的准确率为71.74%,特异性为76.67%,灵敏度为62.5%。肿瘤大小和分化程度与过度分期和分期不足相关。[结论] 对早期胃癌浸润深度的诊断,超声内镜具备临床应用价值。肿瘤大小、病理分化程度影响术前超声内镜分期的准确性。
英文摘要:
      Abstract:[Purpose] To investigate the accuracy of endoscopic ultrasound(EUS) for determination of invasive depth of early gastric cancer,and to analyze the related factors affecting the accuracy.[Methods] The data of 138 patients who accepted examination with EUS and staged as T1,as early gastric cancer from 2012 to 2013 were analyzed retrospectively. The results of EUS with pathology diagnosis for submucosal invasion were compared,and the related factors affecting the accuracy of EUS staging were analyzed.[Results] Of 138 cases of early gastric cancer,EUS determined submucosal invasion with an accuracy of 71.74%,specificity of 76.67%,sensitivity of 62.5%.Tumor size and tumor differentiation were associated with the over-staged and under-staged. [Conclusion] EUS is useful for evaluating the depth of early gastric cancer invasion. Tumor size and pathological differentiation could cause incorrect staging by endoscopic ultrasonography.
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