| 杨 敏,王延风,徐海燕.中晚期原发性肝癌住院患者死亡危险因素分析[J].中国肿瘤,2016,25(6):438-441. |
| 中晚期原发性肝癌住院患者死亡危险因素分析 |
| An Analysis of Risk Factors of Fatal Inpatients with Advanced Primary Hepatic Carcinoma |
| 投稿时间：2016-03-19 |
| DOI：10.11735/j.issn.1004-0242.2016.06.A008 |
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| 中文关键词: 原发性肝癌 死亡 危险因素 |
| 英文关键词:primary hepatic carcinoma death risk factors |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 探讨影响中晚期原发性肝癌住院患者死亡的危险因素。［方法］ 回顾性分析83例中晚期原发性肝癌住院死亡患者的资料，从性别、年龄、乙型肝炎病毒感染、门静脉癌栓、Child-Pugh分级等方面研究影响患者死亡的因素，采用Cox比例风险回归模型进行单因素和多因素分析。［结果］ 全组患者中位生存时间为12.0月。Cox回归模型分析结果显示：乙型肝炎病毒感染、肿瘤治疗方式、门静脉癌栓、ECOG评分及Child-Pugh分级与中晚期原发性肝癌的预后相关。［结论］ 乙型肝炎病毒感染、门静脉癌栓、Child-Pugh分级是中晚期原发性肝癌的独立预后因素。 |
| 英文摘要: |
| Abstract：［Purpose］ To explore the risk factors of fatal inpatients with advanced primary hepatic carcinoma. ［Methods］ The clinic data of 83 cases with advanced primary hepatic carcinoma who died in hospital was retrospectively analyzed，and investigate from the gender，age，history of chronic hepatitis B，portal vein tumor thrombus，Child-Pugh classification and othen influence factors for survival，according to Cox proportional hazard model. ［Results］ The median survival for all patients was 12 months. The results of Cox regression analysis indicated that the Hepatitis B virus infection，treatment，portal vein tumor thrombus，ECOG score and Child-Pugh grade were significant prognostic factors. ［Conclusions］ The Hepatitis B virus infection，portal vein tumor thrombus and Child-Pugh grade are independent factors influencing fatal inpatients with advanced primary hepatic carcinoma. |
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