| 中文关键词: 肺癌 危险因素 流行病学 |
| 英文关键词:risk factors lung neoplasms epidemiology |
| 基金项目:淮河流域癌症综合防治项目（131080003） |
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| 中文摘要: |
| 摘 要：国内外有大量文献和统计研究确定了肺癌相关危险因素。其中最肯定的危险因素为吸烟，但引起肺癌的其他危险因素研究结果却很不一致，如雌激素、饮食、慢性呼吸系统疾病等。全文结合国际癌症研究所有关人类致癌物评估的结果，对近年来肺癌危险因素的研究进展，尤其是我国人群的肺癌研究进行阐述。我国云南锡矿工职业暴露和筛查队列、云南宣威肺癌高发现场、上海女性健康队列等揭示了吸烟、室内燃煤污染、职业性氡暴露、非吸烟女性雌激素与肺癌的关系。 |
| 英文摘要: |
| Abstract：A large number of studies have reported the possible related risk factors of lung cancer. The major cause of lung cancer is tobacco smoking. However，evidence from several cohort and case-control studies published on other risk factors of lung cancer，such as reproductive and hormonal factors，dietary intake，COPD，which has indicated that these factors are inconsistent associated with lung cancer. In this paper，considering the evaluation result of carcinogenic risks to human from IARC，recent advances about the role of the main risk factors，especially in Chinese population during the development of lung cancer have been reviewed. It has shown that the cohort study among tin miners in Yunnan province，high incidence areas study of lung cancer in Xuanwei，the Shanghai Women’s Health Study made contribution to the relations between lung cancer and tobacco smoking，household coal use，occupational radon exposure and reproductive and hormonal factors in female nonsmokers. |
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