李辉章,杜灵彬,朱 陈.2013年浙江省肿瘤登记地区恶性肿瘤发病与死亡分析[J].中国肿瘤,2017,26(1):8-17.
2013年浙江省肿瘤登记地区恶性肿瘤发病与死亡分析
Analysis of Cancer Incidence and Mortality in Zhejiang Cancer Registries,2013
投稿时间:2016-12-09  
DOI:10.11735/j.issn.1004-0242.2017.01.A002
中文关键词:  肿瘤登记  恶性肿瘤  发病率  死亡率  浙江
英文关键词:cancer registration  cancer  incidence  mortality  Zhejiang
基金项目:浙江省自然科学基金(LY15H260001)
作者单位
李辉章 浙江省癌症中心浙江省肿瘤防治办公室 
杜灵彬 浙江省癌症中心浙江省肿瘤防治办公室 
朱 陈 浙江省癌症中心浙江省肿瘤防治办公室 
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中文摘要:
      摘 要:[目的] 分析2013年浙江省肿瘤登记地区恶性肿瘤发病与死亡情况。[方法] 收集2013年浙江省9个肿瘤登记处上报的恶性肿瘤发病、死亡及人口资料,各质量评价指标分别为:病理学诊断比例(MV%)为73.69%,只有死亡医学证明书比例(DCO%)为0.51%,死亡/发病比(M/I)为0.54,诊断依据不明比例(UB%)为0.75%,未指明部位及原发部位不明(继发)比例(O&U%)为4.15%。计算发病和死亡的粗率、标化率、累积率(0~74岁)、年龄别率、地区别率以及前10位恶性肿瘤发病与死亡顺位等。采用2000年中国标准人口年龄构成和Segi’s世界标准人口年龄构成计算年龄标准化率。[结果] 2013年浙江省9个肿瘤登记地区共报告新发恶性肿瘤病例40 459例,粗发病率为343.31/10万,中标率为210.28/10万,世标率为201.99/10万。男性发病率高于女性,城市地区发病率高于农村地区。恶性肿瘤发病在40岁以后快速上升,在80~84岁年龄组达到高峰。发病前10位恶性肿瘤依次为肺癌、甲状腺癌、结直肠癌、胃癌、肝癌、女性乳腺癌、食管癌、胰腺癌、宫颈癌和前列腺癌,城乡恶性肿瘤发病谱存在差异。2013年因恶性肿瘤死亡病例21 880例,粗死亡率为185.66/10万,中标率为99.77/10万,世标率为98.59/10万。男性死亡率高于女性,农村地区死亡率高于城市地区。恶性肿瘤死亡在45岁以后快速上升,在85岁以上年龄组达到高峰。死亡前10位恶性肿瘤依次为肺癌、肝癌、胃癌、结直肠癌、胰腺癌、食管癌、白血病、淋巴瘤、脑肿瘤和胆囊癌。[结论] 肺癌、消化系统恶性肿瘤和女性乳腺癌是浙江省肿瘤防治工作的重点癌种。甲状腺癌的过度诊治问题不容忽视。
英文摘要:
      Abstract:[Purpose] To analyze the cancer incidence and mortality in Zhejiang cancer registries in 2013. [Methods] The incidence,mortality and population data were collected and evaluated from 9 population-based cancer registries of Zhejiang Province. The quality indicators such as the percentage of morphology verified(MV%),mortality to incidence ratio(M/I),the percentage of cancer cases identified with death certification only (DCO%),the percentage of uncertified cancer (UB%) and the percentage of cancer with undefined or unknown primary site (secondary) (O&U%) were 73.69%,0.54,0.51%,0.75% and 4.15%,respectively. Cancer incidence and mortality crude rate,age-standardized rate,age-specific and region-specific rate,cumulative rate and proportion of top 10 cancers were calculated. Chinese population census in 2000 and Segi’s population were used for calculating age-standardized incidence or mortality. [Results] A total of 40 459 newly diagnosed cancer cases were reported in 2013. The crude incidence rate in Zhejiang cancer registration areas was 343.31/105;the age-standardized incidence rates by Chinese standard population (ASR China) and by world standard population(ASR world) were 210.28/105 and 201.99/105,respectively. The incidence in male was higher than that in female,and the incidence in urban areas was higher than that in rural areas. Cancer incidence increased rapidly after the age of 40 years and reached the peak at the age group of 80~84 years. The top 10 incident cancers were lung,thyroid,colorectum,stomach,liver,breast(female),esophagus,pancreas,cervix and prostate cancer. There were 21 880 cancer deaths reported in 2013. The crude mortality rate in Zhejiang cancer registration areas was 185.66/105;the mortality(ASR China and ASR world) was 99.77/105 and 98.59/105,respectively. The mortality in males was higher than that in females,and the mortality in rural areas was higher than that in urban areas. Cancer mortality increased rapidly after the age of 45 years and reached the peak at the age group of 85+ years. Lung cancer,liver cancer,stomach cancer,colorectum cancer,pancreas cancer,esophagus cancer,leukemia,lymphoma,brain tumors and gallbladder cancer were most fatal cancer deaths. [Conclusion] Lung cancer,digestive system malignancies and female breast cancer are main cancers that should be focused on in the prevention and control of cancer. Overdiagnosis and overtreatment of thyroid cancer can not be neglected.
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