| 刘曙正,曹小琴,于 亮.2003~2012年林州市胃癌发病、生存及患病分析[J].中国肿瘤,2018,27(3):181-185. |
| 2003~2012年林州市胃癌发病、生存及患病分析 |
| Incidence and Survival of Gastric Cancer in Linzhou City During 2003~2012 |
| 投稿时间：2017-04-06 |
| DOI：10.11735/j.issn.1004-0242.2018.03.A004 |
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| 中文关键词: 胃肿瘤 发病率 生存率 患病率 河南 |
| 英文关键词:gastric neoplasms incidence survival rate prevalence rate Henan |
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| 中文摘要: |
| 摘 要：［目的］ 分析2003~2012年林州市不同部位胃癌发病及生存状况，了解当地胃癌发病趋势和疾病负担。［方法］从林州市肿瘤登记处抽取2003~2012年全部胃癌发病个案记录和人口数据，计算不同性别、部位的胃癌发病率。按世界标准人口（Segi’s）年龄构成计算世界人口结构标化发病率（世标率）。采用Joinpoint模型对2003~2012年胃癌的世标率进行回归分析。应用Kaplan-Meier方法计算5年生存率。［结果］ 2003~2012年间，林州市胃癌新发病例7591例，发病率为73.87/10万，其中贲门癌新发病例4948例，占65.18%。2003年林州市胃癌世标率为78.67/10万，2012年世标率为69.83/10万，世标率下降了11.23%。Joinpoint模型回归分析结果显示，胃癌发病率在2003~2012年间每年下降1.2%（95%CI：0.4~2.1），女性胃癌发病率在2003~2012年间每年下降2.8%（95%CI：0.4~5.1），不明部位胃癌发病率在2005~2012年间每年下降12.6%（95%CI：5.1~19.4）。胃癌的5年生存率为29.3%(95%CI：28.2~30.3)，胃癌5年患病率为196.89/10万。［结论］ 林州市胃癌的发病率呈下降趋势，生存率较以往有所提高，胃癌疾病负担依然较重。胃癌的主要发病部位为贲门。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and survival of gastric cancer in Linzhou city during 2003～2012. ［Methods］ The new cases of gastric cancer and population data during 2003～2012 were collected from Linzhou Cancer Registry. Incidence rate was calculated by gender and sites. Age standardized incidence rate was calculated with world Segi’s population and analyzed with Joinpoint regression model. The 5-year survival rate was calculated with Kaplan-Meier model. ［Results］ There were 7591 new gastric cancer cases during 2003～2012 in Linzhou city with a crude incidence rate of 73.87/105. Among all gastric cancer cases，4948(65.18%) were diagnosed as cardia cancer. The age standardized incidence rate by world standard population(ASIRW) was 78.67/105 in 2003，69.83/105 in 2012，decreased with 11.23%. Joinpoint regression model showed that estimated annual percentage change(EAPC) decreased 1.2%（95%CI：0.4～2.1）for gastric cancer between 2003 and 2012. The EAPC decreased 2.8%（95%CI：0.4～5.1）for gastric cancer in females and 12.6%（95% CI：5.1～19.4）for gastric cancer of unspecific site between 2005 and 2012. The 5-year survival rate of gastric cancer was 29.3%（95%CI：28.2～30.3）. The 5-year prevalence of gastric cancer was 196.89 per 100 000. ［Conclusion］ Gastric cancer had a decreasing trend and survival rate was improving in Linzhou city during 2003 to 2012. But gastric cancer is still one of the major disease burden in Linzhou city. The major site of gastric carcinoma is cardia. |
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