| 王巧燕,彭 慧,黄 芳.上海市嘉定区2013～2017年大肠癌筛查结果分析[J].中国肿瘤,2018,27(9):647-651. |
| 上海市嘉定区2013～2017年大肠癌筛查结果分析 |
| Results of Colorectal Cancer Screening in Shanghai Jiading District，2013～2017 |
| 投稿时间：2018-06-07 |
| DOI：10.11735/j.issn.1004-0242.2018.09.A002 |
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| 中文关键词: 大肠癌 筛查 早诊早治 上海 |
| 英文关键词:colorectal cancer screening early diagnosis and treatment Shanghai |
| 基金项目:上海市卫生和计划生育委员会科研课题（20154Y0158） |
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| 摘要点击次数: 2024 |
| 全文下载次数: 516 |
| 中文摘要: |
| 摘 要：［目的］ 分析评价上海市嘉定区大肠癌筛查项目的效果。［方法］ 采用危险度评估问卷调查结合粪便隐血试验（FOBT）两步初筛模式，初筛阳性提示为大肠癌高危人群，建议肠镜检查。收集和整理2013～2017年上海市嘉定区大肠癌初筛及肠镜检查结果。［结果］ 5年间共计完成大肠癌初筛151 824人次，男性占比低于女性，且50～54岁及70～74岁年龄组占比较低。初筛阳性率24.01%，其中肠镜检查顺应性仅为29.42%，男性肠镜检查顺应性显著高于女性，且高年龄组的肠镜检查顺应性较低。检出大肠癌218例，早期比例为38.06%，其中男性及高年龄组人群大肠癌及癌前病变的检出率较高。初筛FOBT阳性居民较危险度评估阳性居民的肠镜检查顺应性及大肠癌检出率高。［结论］ 大肠癌筛查项目通过初筛及肠镜检查，显著提高了大肠癌早期及癌前病变的检出率，将对降低大肠癌的死亡率及延长生存时间具有重要意义。然而初筛阳性居民的肠镜检查顺应性较低的问题将是未来大肠癌筛查工作的重点。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of colorectal cancer screening project in Jiading district of Shanghai. ［Methods］ A two-step colorectal cancer screening project was conducted in Shanghai Jiading district from 2013 to 2017. The questionnaire assessment and fecal occult blood test (FOBT) was used for primary screening，and the subjects identified as high-risk in primary screening were recommended to undergo colonoscopy. The results of primary screening and colonoscopy were analyzed. ［Results］ A total of 151 824 subjects completed colorectal cancer screening in 5 years. The proportion of males was lower than that of females，and the age groups of 50～54 and 70～74 accounted for a relatively lower proportion. The positive rate of primary screening was 24.01%，of which the compliance rate of colonoscopy was only 29.42%. The colonoscopy compliance rate of males was significantly higher than that of females and lower in the high age group. Among 10 722 colonoscopic examinations 218 cases of colorectal cancer were detected，and 38.06% were at early stage. The detection rate of colorectal cancer and precancerous lesions was high among males and high-age group. The compliance of colonoscopy and of colorectal cancer were higher among subjects with positive FOBT than those with positive questionnaire risk assessment. ［Conclusion］ The colorectal cancer screening project with two-step model significantly improves the detection rate of early colorectal cancer and precancerous lesions. However，the low compliance of colonoscopy is concerned and should be the focus for future screening programs. |
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