| 杜 君,郑荣寿,庄建辉.我国食管癌疾病负担与国家自然科学基金基础研究资助情况的相关性分析[J].中国肿瘤,2019,28(4):246-251. |
| 我国食管癌疾病负担与国家自然科学基金基础研究资助情况的相关性分析 |
| Association Between Disease Burden of Esophageal Cancer and Basic Research Funding by NSFC |
| 投稿时间：2018-12-10 |
| DOI：10.11735/j.issn.1004-0242.2019.04.A002 |
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| 中文关键词: 食管肿瘤 发病率 死亡率 国家自然科学基金 |
| 英文关键词:esophageal neoplasms incidence mortality NSFC |
| 基金项目:国家重点研发计划（2018YFC1312100）； |
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| 中文摘要: |
| 摘 要：［目的］ 分析我国食管癌疾病负担与国家自然科学基金资助情况的相关性。［方法］ 收集全国肿瘤登记处上报的2006~2014年食管癌发病、死亡数据，计算食管癌发病率和死亡率，并按地区（城市/农村）、性别和年龄进行分层分析，采用Segi’s世界标准人口年龄构成作为标准人口计算年龄标化发病率和死亡率，估算2014年全国食管癌疾病负担；在国家自然科学基金委ISIS系统查询2010~2018年度国家自然科学基金医学科学部在食管癌基础研究领域的资助信息。［结果］ 2014年全国食管癌发病估计约25.78万，死亡估计约19.30万；2014年全国食管癌发病粗率为18.85/10万，世标率12.17/10万，死亡粗率为14.11/10万，世标率8.75/10万。国家自然科学基金委资助方面，2010~2018年国家自然科学基金委医学科学部共资助食管癌相关研究477项，总经费21 494万元，其中医学科学部七处（H16）共资助食管癌相关研究442项，总经费达到19 965万元，无论是资助项目数还是资助金额都在医学科学部七处资助总数的3%左右，且与食管癌疾病负担并无相关性。［结论］ 食管癌作为中国高发特色恶性肿瘤，尽管近年来发病和死亡均有下降，但是疾病负担依然严重，而国家在食管癌基础研究方面的投入与其疾病负担并不对应，建议加大科研投入，为食管癌的防控工作提供科技支撑。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the association between the disease burden of esophageal cancer and the basic research in esophageal cancer supported by National Natural Science Foundation of China (NSFC). ［Methods］ Registration data on esophageal cancer from 2006 to 2014 were obtained from cancer registries of China．Incidence and mortality stratified by areas，gender and age groups were analyzed. The Segi’s population was applied for the age-standardized rates. Esophageal cancer studies supported by Department of Health Sciences of NSFC were searched from the ISIS system. ［Results］ The new cases of esophageal cancer were 257 800 and death cases of esophageal cancer were 193 000 in 2014. The crude cancer incidence was 18.85/105，and age-standardized incidence rate by Segi’s population was 12.17/105. The crude cancer mortality was 14.11/105 and age-standardized mortality rates adjusted by Segi’s population was 8.75/105. Department of Medical Sciences funded 447 projects for esophageal cancer research with 214.94 million RMB between 2010 and 2018. The funding for esophageal cancer study by Division Ⅶ of Health Sciences was stable，accounting for about 3% of the total funding of Division Ⅶ. ［Conclusion］ Esophageal cancer is one of the most common cancer in China，and is a priority in the cancer prevention and treatment．But the research input is less than needed. In order to support the prevention and control of esophageal cancer，we should find the interesting breakthrough and continue to increase scientific research input. |
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