| 雷 林,尚庆刚,刘维耿.深圳市2001～2015年甲状腺癌发病现状和趋势分析[J].中国肿瘤,2019,28(7):504-508. |
| 深圳市2001～2015年甲状腺癌发病现状和趋势分析 |
| Incidences and Epidemiologic Trends of Thyroid Cancer in Shenzhen，2001~2015 |
| 投稿时间：2019-01-07 |
| DOI：10.11735/j.issn.1004-0242.2019.07.A005 |
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| 中文关键词: 甲状腺癌 发病率 趋势分析 肿瘤登记 广东 |
| 英文关键词:thyroid cancer incidence trend cancer registration Guangdong |
| 基金项目:深圳市科技计划（JCYJ20170413102320786） |
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| 中文摘要: |
| 摘 要：［目的］ 探讨2001～2015年深圳居民甲状腺癌的流行现状和发病趋势。［方法］ 根据深圳市肿瘤登记处收集的2001～2015年户籍居民甲状腺癌发病数据和相应年份的人口资料，计算甲状腺癌发病粗率，以及标准化人口年龄调整发病率（中国人口标化率和世界人口标化率），利用Joinpoint软件进行趋势分析。［结果］ 2001～2015年深圳市肿瘤登记处共登记甲状腺癌4309例，粗发病率12.91/10万，中标率为9.50/10万，世标率为10.76/10万，0～74岁累积率为1.02%，35～64岁截缩率为22.93/10万。从性别分布来看，女性发病率明显高于男性，男女发病比为1∶3.03。从时间趋势上看，甲状腺癌发病率呈上升趋势，世标率从2001年的3.55/10万上升至2015年的17.97/10万，APC为11.33%（P<0.01），除65岁以上年龄组外，其余各组均呈现上升趋势。甲状腺癌患者平均发病年龄（41.3±12.0）岁，发病年龄中位数为40.0岁，发病年龄高峰为50~54岁年龄组。［结论］ 深圳市甲状腺癌近年来呈快速上升趋势，政府部门需制定针对性政策措施，遏制甲状腺癌的过快增长。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and epidemiologic trends of thyroid cancer in Shenzhen during 2001 to 2015. ［Methods］ The thyroid cancer data were collected from Shenzhen Cancer Registry. The crude incidence rate，age-standardized incidence rate by Chinese standard population(ASR China) and age-standardized incidence rate by world standard population(ASR world) of thyroid cancer were calculated. The annual percentage change(APC) of the incidence was analyzed by Joinpoint regression. ［Results］ There were 4039 new cases of thyroid cancer registered by Shenzhen Cancer Registry from 2001 to 2015. The crude incidence rate was 12.91/105，with ASR China of 9.50/105 and ASR world of 10.76/105. The cumulative incidence rate(0～74 years) was 1.02%，and the truncated incidence rate(35～64 years) was 22.93/105. The incidence for females was significantly higher than that for males，with a sex ratio of 1∶3.03. During 2001 to 2015，the ASR world of thyroid cancer was increased from 3.55/105 to 17.97/105(APC=11.33%，P<0.01). The age specific incidence increased in all age groups except the people over the age of 65. The mean age of onset of thyroid cancer was(41.3±12.0) years，with median age of 40.0，and the peak age of onset was 50～54 years. ［Conclusion］ There is an increasing trend of thyroid cancer in Shenzhen from 2010 to 2015. |
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