| 贺红英,阳志军,曾定元.广西三甲医院妇科恶性肿瘤住院患者调查分析[J].中国肿瘤,2019,28(9):672-679. |
| 广西三甲医院妇科恶性肿瘤住院患者调查分析 |
| Epidemiological Investigation of Inpatients with Gynecological Malignancies in Guangxi Zhuang Autonomous Region |
| 投稿时间：2018-11-07 |
| DOI：10.11735/j.issn.1004-0242.2019.09.A007 |
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| 中文关键词: 女性生殖器肿瘤 构成比 住院患者 广西 |
| 英文关键词:female genital neoplasms proportion inpatients Guangxi |
| 基金项目:广西科学研究与技术开发计划项目(14124004-1-24) |
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| 中文摘要: |
| 摘 要：［目的］了解广西壮族自治区妇科恶性肿瘤住院患者的构成特点及变化趋势。［方法］对1985～2011年度广西壮族自治区23家三甲医院收治的16 123例妇科恶性肿瘤患者的临床资料进行统计分析。［结果］ 收治住院排在前4位的分别是宫颈癌、卵巢恶性肿瘤、子宫内膜癌、妊娠滋养细胞肿瘤。宫颈癌的构成比呈上升趋势，从1985～1989年度的17.48%上升至2010～2011年度的56.74%（P＜0.01）；妊娠滋养细胞肿瘤呈下降的趋势，从 30.69%下降到1.75%（P＜0.01）；卵巢恶性肿瘤、子宫内膜癌、外阴阴道恶性肿瘤、子宫肉瘤等，无显著统计学意义（P＞0.05）。宫颈癌的好发年龄从≥60岁前移至＜40岁，呈年轻化态势；子宫内膜癌＜60岁的各年龄段患者构成比有所上升，也存在年轻化态势；卵巢恶性肿瘤及妊娠滋养细胞肿瘤患者的好发年龄无明显改变。卵巢恶性肿瘤和子宫内膜癌等其他妇科恶性肿瘤发病地域城镇高于农村，而妊娠滋养细胞肿瘤农村高于城镇；前10年宫颈癌患者主要集中于城镇，构成比67.10%，后10年却主要集中在农村，构成比52.60%。宫颈癌、子宫内膜癌、外阴阴道恶性肿瘤、子宫肉瘤和输卵管癌收治的大部分为早期患者（Ⅰ～Ⅱ期），分别占66.24%、67.32%、51.40%、73.78%及67.90%；而卵巢恶性肿瘤及妊娠滋养细胞肿瘤多数为中晚期（Ⅲ～Ⅳ期）患者，分别占56.26%及53.11%。［结论］ 应重点加强对宫颈癌的普查防治工作，加大对卵巢恶性肿瘤及妊娠滋养细胞肿瘤的肿瘤标志物、诊治方法的研究力度，提高早期诊治率。 |
| 英文摘要: |
| Abstract：［Purpose］ To investigate the epidemiological characteristics of inpatients with gynecologic malignant tumors in Guangxi Zhuang Autonomous Region. ［Methods］ Clinical data of 16 123 inpatients who suffered from gynecologic malignant tumors in 23 Third-grade class-A hospitals from 1985～2011 in Guangxi Zhuang Autonomous Region were analyzed. ［Results］ The top 4 types of malignant tumors were cervical cancer，ovarian cancer，endometrial cancer，gestational trophoblastic neoplasia according to the constituent ratios of the tumors. The constituent ratio of cervical cancer patients increased from 17.48% during the 1985～1989 to 56.74% during the 2010～2011(P＜0.01)，while the constitutient ratio of gestational trophoblastic neoplasia decreased from 30.69% to 1.75%(P＜0.01). The constituent changes of ovarian cancer，endometrial cancer，vulvar and vaginal cancer，and sarcoma of uterus were not significant(P＞0.05). The age of cervical cancer patients dropped from≥60 years to＜40 years；the constituent ratio of endometrial cancer patients aged＜60 years was also increased；the age of patients with ovarian cancer and gestational trophoblastic neoplasia was stable. Ovarian cancer and endometrial cancer were mainly prevalent in urban areas，while gestational trophoblastic neoplasia was mainly in rural areas. Cervical cancer was mainly prevalent among urban residents in the earlier decade with a constitutive ratio of 67.10%，while it shifted to rural areas in the later decade with a constitutive radio of 52.60%. Majority of patients with cervical cancer，endometrial cancer，vulvar and vagina cancer，sarcoma of uterus and fallopian tube cancer were stage Ⅰ～Ⅱ，accounting for 66.24%，67.32%，51.40%，73.78% and 67.90%，respectively，while patients with ovarian cancer and gestational trophoblastic neoplasia were mainly in the stage Ⅲ and stage Ⅳ，accounting for 56.26% and 53.11% respectively. ［Conclusions］ The survey suggests that screening program of cervical cancer should be strengthened，and tumor markers，new methods of diagnosis and treatment of ovarian cancer and gestational trophoblastic neoplaisa should be further studied. |
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