| 闫贻忠,王新宇,陈 瑜.2010~2017年新疆石河子市女性乳腺癌流行趋势分析[J].中国肿瘤,2019,28(9):689-693. |
| 2010~2017年新疆石河子市女性乳腺癌流行趋势分析 |
| Time Trend of Female Breast Cancer in Xinjiang Shihezi Region，2010～2017 |
| 投稿时间：2018-07-02 |
| DOI：10.11735/j.issn.1004-0242.2019.09.A009 |
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| 中文关键词: 乳腺癌 女性 发病率 死亡率 时间趋势 新疆 |
| 英文关键词:breast cancer female incidence mortality time trend Xinjiang |
| 基金项目:新疆生产建设兵团重大公共卫生专项（20100409） |
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| 中文摘要: |
| 摘 要：［目的］ 分析新疆石河子市2010～2017年女性乳腺癌发病与死亡流行趋势。［方法］ 根据石河子市2010～2017年肿瘤登记资料，计算女性乳腺癌发病率、死亡率及其标化率，并采用年度变化百分比(APC)模型分析其时间和年龄趋势。［结果］ 2010～2017年石河子市女性乳腺癌发病1221例，发病率为52.95/10万，中标率40.58/10万，世标率33.59/10万；死亡478例，死亡率为20.73/10万，中标率15.58/10万，世标率12.92/10万。女性乳腺癌发病率从2010年的27.41/10万上升到2017年的44.17/10万，增加了61.15%，APC为10.00%(95%CI：4.93%～26.96%，P>0.05)；死亡率从2010年的11.60/10万上升到2017年的30.45/10万，增加了162.50%，APC为14.56%(95%CI：0.14%～31.06%，P<0.05)。乳腺癌50～54岁发病率和65～69岁死亡率上升有统计学意义，APC分别为19.46%和12.58%。［结论］ 2010～2017年石河子女性乳腺癌发病、死亡水平增长明显，且发病和死亡人群年轻化，应加强乳腺癌的早诊早治，尤其是中年女性乳腺癌防控工作亟待加强。 |
| 英文摘要: |
| Ａbstract：［Purpose］ To analyze the time trends of female breast cancer in Xinjiang Shihezi region during 2010～2017. ［Methods］ The crude and standardized incidence，mortality rates of female breast cancer were calculated from the data of Cancer Registry in Shihezi，and the model of annual percent change(APC) was used to analyze the time trends of the rates. ［Results］ A total of 1221 new cases of female breast cancer were registered in Shihezi during 2010～2017，the crude incidence was 52.95/105，the incidence of age-standardized rate by Chinese standard population(ASRC) was 40.58/105，and the incidence of age-standardized rate by world standard population(ASRW) was 33.59/105. There were 478 cases died from breast cancer during the same period，the crude mortality was 20.73/105，the mortality of ASRC was 15.58/105，and the mortality of ASRW was 12.92/105. The incidence of female breast cancer rose from 27.41/105 in 2010 to 44.17/105 in 2017，increasing by 61.15%，APC was 10.00%(95%CI：4.93%～26.96%，P>0.05)，and mortality increased from 11.60/105 in 2010 to 30.45/105 in 2017，with an increase of 162.50%，APC was 14.56%(95%CI：0.14%~31.06%，P<0.05). The incidence of female breast cancer in age group 50～54 and mortality of female breast cancer in age group 65～69 increased significantly，with APC of 19.46% and 12.58%，respectively. ［Conclusion］ During 2010～2017，the incidence and mortality of female breast cancer in Shihezi increased significantly，early diagnosis and treatment of breast cancer should be strengthened，especially among middle-aged women. |
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