| 李 锋,毛友生.病理亚型在Ⅰ期肺腺癌手术方式选择中作用的研究进展[J].中国肿瘤,2019,28(10):786-791. |
| 病理亚型在Ⅰ期肺腺癌手术方式选择中作用的研究进展 |
| Guidance of Pathological Subtypes for Choice of Surgical Approaches in Lung Adenocarcinoma Stage Ⅰ |
| 投稿时间：2019-03-29 |
| DOI：10.11735/j.issn.1004-0242.2019.10.A012 |
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| 中文关键词: 肺腺癌 手术方式 病理学 |
| 英文关键词:lung adenocarcinoma surgical approach pathology |
| 基金项目: |
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| 中文摘要: |
| 摘 要：诊断技术的进步使越来越多的Ⅰ期肺腺癌被早期发现。手术切除是Ⅰ期肺腺癌的首选治疗方式。2011年，新的肺腺癌病理亚型分类标准由国际肺癌研究会/美国胸科学会/欧洲呼吸学会提出。2015年，气道内播散这一新的病理学特征被引入最新版的WHO分型。近年来的研究显示病理亚型在影响Ⅰ期肺腺癌患者预后的同时对手术方式选择也有重要的指导作用。既往回顾性研究提示术中冰冻病理在诊断肺腺癌病理亚型方面有着较好的准确性，未来可以用于指导Ⅰ期肺腺癌手术方式的选择。 |
| 英文摘要: |
| Abstract：More stageⅠ lung adenocarcinomas are detected early due to the advances in diagnostic techniques. Surgical resection is the first choice of treatment for stageⅠ lung adenocarcinoma. In 2011，a new adenocarcinoma classification was proposed by International Association for the Study of Lung Cancer(IASLC)/American Thoracic Society(ATS)/European Respiratory Society(ERS). And in 2015，spread through air spaces(STAS) as a new pathological feature was introduced in the latest WHO classi cation. Recent studies have shown that pathological subtypes have an effect on both the prognosis and the choice of surgical approaches in patients with stageⅠlung adenocarcinoma. Re-trospective studies indicated that intraoperative frozen section had a relatively good accuracy for diagnosing the pathological subtypes of lung adenocarcinoma and it may be used to guide the surgical approaches for stageⅠlung adenocarcinoma in the future. |
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