李辉章,杜灵彬,李其龙.浙江省海宁和嘉善肿瘤登记地区恶性肿瘤生存分析[J].中国肿瘤,2020,29(1):14-21.
浙江省海宁和嘉善肿瘤登记地区恶性肿瘤生存分析
Cancer Survival in Haining and Jiashan Cancer Registry Areas of Zhejiang Province
中文关键词  修订日期:2019-12-04
DOI:10.11735/j.issn.1004-0242.2020.01.A003
中文关键词:  浙江  肿瘤登记  恶性肿瘤  相对生存率
英文关键词:Zhejiang  cancer registry  cancer  relative survival rate
基金项目:科技部重大专项精准医学研究(2016YFC0901405);
作者单位
李辉章 中国科学院肿瘤与基础医学研究所/中国科学院大学附属肿瘤医院/浙江省肿瘤医院 
杜灵彬 中国科学院肿瘤与基础医学研究所/中国科学院大学附属肿瘤医院/浙江省肿瘤医院 
李其龙 嘉善县肿瘤防治所 
摘要点击次数: 2019
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中文摘要:
      摘 要:[目的] 分析浙江省海宁和嘉善肿瘤登记地区恶性肿瘤相对生存率。[方法] 以海宁市和嘉善县肿瘤登记处收集上报的2003年1月1日至2013年12月31日期间新发的31 898例肿瘤登记病例作为研究对象,随访截止日期为2016年4月15日。采用Stata软件strs程序包中EdererⅡ模型计算2003—2006、2007—2010和2011—2014三个不同时期的恶性肿瘤的相对生存率,并对癌种、性别和年龄进行亚组分析。[结果] 2003—2006、2007—2010和2011—2014期间,浙江省海宁和嘉善肿瘤登记地区恶性肿瘤5年相对生存率分别为33.6%、38.2%和44.8%,年龄标化的5年相对生存率分别为31.9%、35.6%和37.2%。其中,男性3个时期的5年相对生存率依次为26.9%、28.9%和34.8%,女性依次为43.3%、49.9%和56.8%。胰腺癌、肝癌、肺癌、食管癌和胆囊癌5年相对生存率较低(小于30%),而甲状腺癌、乳腺癌、膀胱癌、肾癌和喉癌等5年相对生存率较高(大于70%)。结直肠癌、子宫体癌、前列腺癌、宫颈癌和脑瘤5年相对生存率增长速度较快,增幅分别为12.8%、13.5%、16.8%、23.6%、38.7%。[结论] 浙江省海宁和嘉善肿瘤登记地区恶性肿瘤5年生存率持续上升,以结直肠癌、宫颈癌为代表的癌种防治效果显著,5年相对生存率已达到或接近发达国家水平。
英文摘要:
      Abstract:[Purpose] To analyze the population-based cancer relative survival in Haining and Jiashan cancer registry areas of Zhejiang province. [Methods]Cancer incident cases were collected from Haining and Jiashan cancer registries. Patients were diagnosed between January 1,2003 and December 31,2013,with last follow-up information at April 15,2016. Statistical analysis was performed on Stata 15.1 software. Strs package was applied to calculate relative survival by Ederer Ⅱ model in three periods (2003—2006,2007—2010 and 2011—2014). The data were stratified by cancer type,gender and age group. [Results] The 5-year cancer relative survival was 33.6% for 2003—2006,38.2% for 2007—2010 and 44.8% for 2011—2014,with age standardized survival of 31.9%,35.6% and 37.2% for corresponding periods. The 5-year cancer relative survival rate in 3 periods was 26.9%,28.9% and 37.2% for males,and 43.3%,49.9% and 56.8% for females.The 5-year relative survival for cancers of the pancreas,liver,lung,esophagus and gallbladder was relatively poor (below 30%);while cancers of the thyroid,breast,bladder,kidney and larynx had fine survival(above 70%). The 5-year relative survival for cancers of the colorectum,uterus,prostate,cervix and brain increased by 12.8%,13.5%,16.8%,23.6%and 38.7%,respectively.[Conclusion]Steady progress in increasing cancer survival has been made over the past few decades in Haining and Jiashan cancer registry areas of Zhejiang province.The 5-year relative survival rates of colorectal and cervical cancers have reached or approached the levels of developed countries in the world.
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