| 中文关键词: 胃肿瘤 筛查 内镜 血清学 |
| 英文关键词:gastric neoplasms screening endoscope serology |
| 基金项目:深圳市医疗卫生三名工程(SZSM 201911015)；国家重点研发计划精准医学研究重点专项（2016YFC0901400） |
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| 中文摘要: |
| 摘 要：胃癌是最常见的消化道肿瘤之一。在我国，胃癌发病率排在恶性肿瘤发病率的第4位，死亡率排第2位，严重威胁着我国人民群众的生命健康。胃癌起病隐匿，早期病变仅限于黏膜及黏膜下层，无明显临床症状，患者就诊时多为晚期，术后5年生存率低于30%。早期胃癌患者经过治疗可使5年生存率达90%以上，因此提高早期胃癌的检出率是改善胃癌预后的重要途径。胃癌的筛查方法主要包括影像学、血清学及内镜检查等，本文对胃癌筛查方法和筛查策略的研究进展进行综述。 |
| 英文摘要: |
| Abstract：Gastric cancer(GC) is one of the most common gastrointestinal tumors. In China，this disease is the fourth most common malignant cancer and second leading cause of cancer death，which seriously threatens the life and health of the people in China. The onset of gastric cancer is insidious. The early lesions are limited within the mucosa and submucosa，without specific and obvious clinical symptoms shown. Disease is usually in late stage at the time of consultation，with a 5-year survival rate of <30%；in contrast patients with early gastric cancer can achieve 5-year survival rate of 90% after treatment. Therefore，increasing the detection rate of early gastric cancer is an important way to improve the prognosis of patients. The screening methods for gastric cancer mainly include imaging，serology and endoscopy. This article reviews the research progress of screening methods and screening strategies for gastric cancer. |
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