何 美,李必波,杜 佳.2012—2016年重庆市城市人群结直肠癌筛查结果分析[J].中国肿瘤,2020,29(6):430-433.
2012—2016年重庆市城市人群结直肠癌筛查结果分析
Analysis of Colorectal Cancer Screening Results Among Urban High Risk Population in Chongqing During 2012—2016
中文关键词  修订日期:2020-02-26
DOI:10.11735/j.issn.1004-0242.2020.06.A005
中文关键词:  结直肠肿瘤  高危人群  筛查  城市  早诊早治  重庆
英文关键词:colorectal neoplasms  high risk population  screening  city  early diagnosis and early treatment  Chongqing
基金项目:重庆市科学技术局科研机构绩效激励引导专项(cstc2018jxjl130058);国家重点研发计划精准医学研究重点专项(2016YFC0901400)
作者单位
何 美 重庆大学附属肿瘤医院/重庆市肿瘤研究所/重庆市肿瘤医院 
李必波 重庆市人民医院/中国科学院大学重庆医院 
杜 佳 重庆大学附属肿瘤医院/重庆市肿瘤研究所/重庆市肿瘤医院 
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中文摘要:
      摘 要:[目的] 分析2012—2016年重庆城市高风险人群结直肠癌筛查情况,为开展癌症早诊早治项目工作提供依据。[方法] 2012—2016年对重庆市4个辖区(沙坪坝、南岸区、渝中区和九龙坡区)中40~69岁户籍人口进行高风险评估,对评估出的结直肠癌高危人群采用全结肠镜、指示性活检技术开展相应的检查,探讨结直肠癌筛查效果。[结果] 4年共计评估出结直肠癌高危人群21 441名,高风险评估率为12.19%;实际参与全结肠镜检查者4110名,总体依从性为19.17%。息肉检出率为19.51%(802/4110),男性息肉检出率(26.73%)明显高于女性(14.33%);随着年龄的增长,息肉检出率逐渐上升,且差异有统计学意义(P<0.01)。有936例患者在结肠镜下取标本进行病理检查,检出结直肠癌9例(0.22%),癌前病变106例(2.58%),非进展期腺瘤341例(8.30%),非瘤性息肉235例(5.72%);每种病变的检出率男性均高于女性,并且随着年龄增长呈上升趋势。[结论] 高危人群中肠道病变检出率男性均明显高于女性,年龄越大检出率越高。男性或年长者是结直肠癌筛查关注的重点,应进一步提高他们在结直肠癌筛查中的依从性。
英文摘要:
      Abstract:[Purpose] To analyze the results of colorectal cancer screening among urban high risk population in Chongqing during 2012-2016.[Methods] The urban residents aged 40~69 years from four districts of Chongqing Municipality(Shapingba,Nanan,Yuzhong,Jiulongpo) participated in the primary screening with questionnaire cancer risk assessment during 2012-2016. The identified high risk individuals of colorectal cancer underwent colonoscopy and biopsy. The results of colorectal cancer screening were evaluated.[Results] Total 21441 high risk individuals were identified by primary assessment during 2012-2016 with a high risk rate of 12.19%. Among them 4110 individuals received the colonoscopy with a compliance rate of 19.17%. The detection rate of colorectal polyps was 19.51%(802/4110),the detection rate of men(26.73%) was significantly higher than that of women(14.33%). And with the increase of age,the detection rate of colorectal polyps was significantly elevated(P<0.01). Among 936 subjects receiving pathological examination,9 cases were diagnosed as colorectal cancer(0.22%),106 cases were diagnosed as colorectal precancerous lesions(2.58%),341 cases were diagnosed as non-progressive adenoma(8.30%) and 235 cases were diagnosed as non-neoplastic polyps(5.72%). The detection rate of colorectal lesions in men was significantly higher than that in women. And with the increase of age,the detection rate of colorectal lesions was significantly elevated. [Conclusion] The detection rate of colorectal lesions in male high risk population is significantly higher than that of females. And with the increase of age,the detection rate of colorectal lesions is significantly elevated. Males and elderly individuals should be the focus on colorectal cancer screening,and the compliancy of colorectal cancer screening need be improved in this population.
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