| 张永辉,朱 健,严永锋.江苏省启东市1972—2016年胰腺癌死亡特征及变化趋势分析[J].中国肿瘤,2020,29(8):586-591. |
| 江苏省启东市1972—2016年胰腺癌死亡特征及变化趋势分析 |
| Pancreatic Cancer Mortality and Trends in Qidong City，1972—2016 |
| 中文关键词 修订日期：2020-03-09 |
| DOI：10.11735/j.issn.1004-0242.2020.08.A005 |
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| 中文关键词: 胰腺肿瘤 死亡率 江苏 |
| 英文关键词:pancreatic cancer mortality Jiangsu |
| 基金项目: |
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| 中文摘要: |
| 摘 要：［目的］ 分析研究启东市1972—2016年胰腺癌的死亡率水平及变化趋势，为胰腺癌的防控策略提供理论依据及参考。［方法］ 胰腺癌死亡病例数据资料来源于以人群为基础的癌症登记系统，计算胰腺癌粗死亡率、中国人口标化率（中标率）、世界人口标化率（世标率）、累积率和截缩率；用Joinpoint 4.1.0软件计算平均年度变化百分比（annual percent change，APC）及其95%可信区间评价胰腺癌死亡率的时间变化趋势。［结果］ 启东市1972—2016年胰腺癌总死亡4112例，占全部癌症死亡的4.16%；粗死亡率为8.13/10万，中标率和世标率分别为5.54/10万和5.51/10万；35~64岁截缩死亡率为7.03/10万；0~74岁累积死亡率为0.66%；胰腺癌死亡的累积风险为0.66%。男性死亡2267例，粗死亡率为9.08/10万，中标率和世标率分别为6.37/10万和6.75/10万；女性死亡1845例，粗死亡率为7.20/10万，中标率和世标率分别为4.77/10万和4.44/10万。45年间胰腺癌粗死亡率的APC平均增加了3.92%（男性为3.94%，女性为3.91%）；中标率的APC平均上升了1.32%（男性为1.06%，女性为1.59%）；世标率的APC平均上升了1.29%（男性为1.13%，女性为1.46%）。胰腺癌死亡率随年龄的增长而升高，男女性均在80~岁组达到高峰。年龄别死亡率显示54岁以下各年龄段死亡率趋势不明显，而55~64岁、65~74岁及≥75岁各年龄段死亡率均呈上升趋势，尤其是≥75岁高龄段死亡率上升趋势最为显著。［结论］ 启东45年来胰腺癌死亡率水平较高，且呈上升趋势，应加以重视。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the mortality and trends of pancreatic cancer in Qidong City from 1972 to 2016. ［Methods］ The data of death cases of pancreatic cancer were collected from the population-based cancer registration system. The crude mortality rate(CR)，age-standardized rate by China population(CASR)，age-standardized rate by world population(WASR)，0~74 years cumulative rate，35~64 years truncated rate were calculated，and annual percentage change(APC) and its 95% confidence interval(95%CI) were analyzed by Joinpoint Regression Program(4.1.0) to evaluate the trends of pancreatic cancer mortality. ［Results］ There were 4112 fatal cases of pancreatic cancer during 1972 to 2016 in Qidong including 2267 males and 1845 females，which accounted for 4.16% of all cancer deaths. The CR，CASR，WASR were 8.13/105，5.54/105 and 5.51/105，respectively. Truncated rate of 35~64 years，cumulative rate of 0~74 years and cumulative risk were 7.03/105，0.66%，0.66%，respectively. The CR，CASR，WASR were 9.08/105，6.37/105，6.75/105 in males，and 7.20/105，4.77/105，4.44/105 in females，respectively. During the 45 years，APC of pancreatic cancer CR was 3.92%，3.94% for men and 3.91% for women；that of CASR was 1.32% ，1.06% for men and 1.59% for women；that of WASR was 1.29%，1.13% for men and 1.46% for women. The mortality rate of pancreatic cancer increased with the age，having reached a high level in the age group of 80~ in both sexes. The increasing trends of mortality in all age groups under 54 years old were not significant，while in age groups of 55~64，65~74 and 75~，the mortality rates showed an upward trends，especially in the 75 and over age group. ［Conclusion］ Among residents in Qidong，pancreatic cancer has a high mortality rate and is remarkably increased during 1972-2016. More attention should be paid to reduce the mortality of pancreatic cancer in Qidong. |
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