| 郑文龙,沈成凤,张 辉.天津市2008—2016年女性乳腺癌发病及死亡趋势分析[J].中国肿瘤,2020,29(8):596-601. |
| 天津市2008—2016年女性乳腺癌发病及死亡趋势分析 |
| An Analysis on the Variation Trends of Female Breast Cancer’s Incidence and Mortality from 2008 to 2016 in Tianjin |
| 中文关键词 修订日期：2019-11-21 |
| DOI：10.11735/j.issn.1004-0242.2020.08.A007 |
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| 中文关键词: 乳腺癌 发病率 死亡率 早死寿命损失年 趋势 女性 天津 |
| 英文关键词:breast cancer incidence mortality years of life lost trend female Tianjin |
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| 中文摘要: |
| 摘 要：［目的］ 分析天津市2008—2016年女性乳腺癌发病、死亡水平和变化趋势，为开展相关预防和研究工作提供参考。［方法］ 基于2008—2016年天津户籍居民肿瘤随访登记数据，计算女性乳腺癌发病率、死亡率、标化率和过早死亡损失寿命年（YLL）等指标，采用Joinpoint回归分析变化趋势。［结果］ 2008—2016年天津市共报告女性乳腺癌新发病例24 180例，占肿瘤新发病例的18.64%（居第2位），报告死亡病例4465例，占肿瘤死亡病例的7.30%（居第4位）；城乡标化发病率比为1.59∶1，标化死亡率比为1.56∶1。2008—2016年天津女性乳腺癌粗发病率（AAPC=5.50%）、标化发病率（AAPC=4.60%）均呈上升趋势（P<0.01）；粗死亡率（AAPC=3.50%）呈上升趋势，标化死亡率未有明显上升趋势（AAPC=1.60%，P>0.05）。2008—2016年天津城区乳腺癌发病率低年龄组增长较快，而死亡率高年龄组增长较快；农村地区乳腺癌发病率各年龄组增长均较快，死亡率以高年龄组增长为主。城区乳腺癌发病高峰在65~69岁年龄组，农村发病高峰在55~59岁年龄组。［结论］ 天津女性乳腺癌发病率仍处于快速上升期，但59岁以下死亡率未见明显上升趋势，乳腺癌防控和治疗取得了一定成效。应进一步开展健康干预和重点人群筛查等预防措施。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality and changing trends of female breast cancer in Tianjin and provide references for research and prevention.［Methods］ Based on the tumor registration data of registered residents from 2008 to 2016 in Tianjin，the incidence rate，mortality rate，age standard rate and years of life lost(YLL) of female breast cancer were calculated. And the trends of the incidence rate and mortality rate were analyzed by Joinpoint regression.［Results］ From 2008 to 2016，a total of 24 180 new cases of female breast cancer were reported in Tianjin，accounting for 18.64%(second) of all new cases，and 4465 deaths were reported，accounting for 7.30%(fourth) of all cancer deaths. The standardized incidence ratio was 1.59∶1 and the standardized mortality ratio was 1.56∶1 between urban and rural areas. From 2008 to 2016，the crude incidence rate(AAPC=5.50%) and standardized incidence rate(AAPC=4.60%) of female breast cancer both had rising trends. The crude mortality rate showed an upward trend(AAPC=3.50%)，while the standardized mortality rate did not show a significant upward trend(AAPC=1.60%，P>0.05). From 2008 to 2016，the incidence of breast cancer in Tianjin urban areas increased rapidly in the young group，while the mortality in the older group increased rapidly.The incidence of breast cancer in rural areas increased rapidly in all age groups，and the mortality rate was mainly increased in high age groups. The incidence peak of breast cancer in urban areas was 65~69 year?鄄old group，and it was 55~59 year?鄄old group in rural areas.［Conclusions］ The incidence rate of female breast cancer in Tianjin is still rising rapidly，but the mortality rate under 59 years old has not showed an obvious increasing trend，which attested that the prevention and treatment of breast cancer have gained results to some extent. The prevention and control strategies such as lifestyle intervention and screening of key groups should be further implemented. |
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