| 丁贤彬,吕晓燕,毛德强.2012—2018年重庆市白血病发病和死亡趋势分析[J].中国肿瘤,2020,29(10):744-750. |
| 2012—2018年重庆市白血病发病和死亡趋势分析 |
| Trends of Incidence and Mortality of Leukemia in Chongqing，2012—2018 |
| 中文关键词 修订日期：2020-03-25 |
| DOI：10.11735/j.issn.1004-0242.2020.10.A005 |
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| 中文关键词: 白血病 发病率 死亡率 年度变化百分比 重庆 |
| 英文关键词:leukemia incidence mortality annual percent change Chongqing |
| 基金项目:西南地区慢病防控科技综合示范研究（2018YFC1311404） |
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| 中文摘要: |
| 摘 要：［目的］ 分析重庆市白血病发病率与死亡率趋势变化，为开展白血病防治提供建议。［方法］ 整理收集2012—2018年重庆市肿瘤登记点白血病发病和死亡的个案资料（ICD-10：C91-C95），统计分析发病率、中国人口标化发病率（ASIRC）、世界人口标化发病率(ASIRW)、年龄别发病率、死亡率、中国人口标化死亡率(ASMRC)、世界人口标化死亡率(ASMRW)、年龄别死亡率和年度变化百分比（APC）。［结果］ 重庆市白血病发病率、中标发病率、世标发病率分别由2012年的8.47/10万、5.59/10万、6.08/10万下降至2018年的4.99/10万、4.21/10万、4.31/10万，APC分别为-7.60%(-9.97%～-5.16%)、-2.27%(-5.73%～1.31%)、-3.25%(-6.57%～0.20%)，其中发病率变化趋势差异有统计学意义（t=2.98，P<0.05）。从2014年开始男性白血病发病率高于女性。白血病各年龄组均有发病，1～9岁与70～79岁出现两个小高峰。重庆市白血病死亡率、中标死亡率、世标死亡率分别由2012年的3.82/10万、 3.27/10万、3.37/10万下降至2018年的3.40/10万、2.72/10万、2.85/10万，APC分别为-2.76%、-5.16%、-4.59%，其中中标死亡率和世标死亡率变化趋势差异有统计学意义（P<0.05）。白血病死亡率男性均高于女性。白血病死亡率各年龄组均有发生，随年龄增长缓慢上升，85+岁年龄组死亡率达到高峰。［结论］ 2012—2018年重庆市白血病发病率与死亡率均较高，但有明显下降趋势，儿童与老年人白血病发病率与死亡率高，应重视儿童和老年人群白血病防治。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends of the incidence and mortality of leukemia in Chongqing from 2012 to 2018. ［Methods］ Cases of leukemia(ICD-10 code：C91-C95) from 2012 to 2018 were collected from cancer registry in Chongqing municipality. The incidence，age-standardized incidence rate by Chinese standard population(ASIRC)，age standardized incidence rate by world standard population(ASIRW)，age specific incidence，mortality，age-standardized mortality rate by Chinese standard population(ASMRC)，age standardized mortality rate by world standard population(ASMRW)，age specific mortality and annual percent change(APC) were calculated. ［Results］ The incidence，ASIRC，ASIRW of leukemia in Chongqing were decreased from 8.47/105，5.59/105，6.08/105 in 2012 to 4.99/105，4.21/105，4.31/105 in 2018，respectively；and the corresponding APC was -7.60% (-9.97%～-5.16%)，-2.27%(-5.73%～1.31%) and -3.25%(-6.57%～0.20%)，respectively. The incidence of leukemia of male residents was higher than that of female residents since 2014. The peak of the incidence of leukemia occurred in age group 1~9 years and 70~79 years，respectively. The mortality，ASMRC and ASMRW of leukemia in Chongqing were decreased from 3.82/105，3.27/105 and 3.37/105 in 2012 to 3.40/105，2.72/105 and 2.85/105 in 2018，respectively；and the corresponding APC was -2.76%，-5.16% and -4.59%，respectively. The mortality of leukemia of male residents was higher than that of female residents. The mortality of leukemia increased with age，the age group above 85 years reached the peak. ［Conclusion］ The incidence and mortality of leukemia in Chongqing is high. However，there are a downward trends from 2012 to 2018. The incidence and mortality of leukemia are high among children and elderly residents，and it should be attached an importance on the preventive measures for pediatric and elderly leukemia. |
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