| 周海茸,王琛琛,韩仁强.2011年与2017年江苏省南京市20岁以上人群归因于饮酒的恶性肿瘤疾病负担分析[J].中国肿瘤,2020,29(12):946-951. |
| 2011年与2017年江苏省南京市20岁以上人群归因于饮酒的恶性肿瘤疾病负担分析 |
| Burden of Malignant Tumors Attributable to Alcohol Use in Nanjing in 2011 and 2017 |
| 中文关键词 修订日期：2020-03-26 |
| DOI：10.11735/j.issn.1004-0242.2020.12.A010 |
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| 中文关键词: 饮酒 人群归因分值 疾病负担 期望寿命 江苏 |
| 英文关键词:alcohol use population attributable fraction burden of disease life expectancy Jiangsu |
| 基金项目:南京市卫生科技发展专项资金（ZKX18049） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2011年与2017年江苏省南京市20岁以上人群归因于饮酒的恶性肿瘤疾病负担和期望寿命损失情况。［方法］ 利用南京市慢性病及其危险因素监测、南京市死因监测和2017年全球疾病负担（GBD）资料，采用人群归因分值（PAF）估算饮酒导致相关恶性肿瘤（包括口腔癌、鼻咽癌、其他咽癌、喉癌、食管癌、肝癌、结直肠癌和乳腺癌）死亡和寿命损失的变化。［结果］ 2017年南京市归因于饮酒的相关恶性肿瘤死亡占全部恶性肿瘤死亡的14.74%，相比于2011年（13.43%），南京市饮酒导致恶性肿瘤死亡的PAF增长9.75%；2017年归因于饮酒的恶性肿瘤死亡例数由2011年的332例上升为428例，标化死亡率由2011年的6.67/10万下降为5.96/10万，过早死亡损失寿命年（YLL）由2011年的9090人年上升为11 260人年，标化YLL率由183.66/10万下降为166.30/10万；2017年饮酒对南京人群造成的恶性肿瘤疾病负担和主要死亡均为食管癌；去除饮酒暴露对期望寿命的影响后，2017年南京市≥20岁居民期望寿命为63.09岁，较全死因期望寿命提高0.11岁，其中男性提高0.19岁，女性提高0.01岁。［结论］ 饮酒是影响南京市居民恶性肿瘤死亡和期望寿命的重要因素，应加强饮酒及相关疾病的预防控制。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the burden of malignant tumors attributed to alcohol use and its impact on life expectancy in people aged 20 years and older in Nanjing in 2011 and 2017. ［Methods］ The data were extracted from Nanjing Chronic Disease and Risk Factor Surveillance(2011，2017)，Nanjing Mortality Surveillance(2011，2017) and 2017 Global Burden of Disease Study(GBD). Based on population attributable fractions(PAF)，the deaths and life expectancy loss of malignant tumors(including lip and oral cavity cancer，nasopharyngeal cancer，other pharyngeal cancer，esophageal cancer，colon and rectal cancer，liver cancer，laryngeal cancer，breast cancer) due to alcohol use were estimated. ［Results］ Deaths attributable to alcohol use accounted for 14.74% of all malignant tumor deaths in 2017，which were increases by 13.43% compared to 2011. The number of deaths caused by related malignant tumor attributed to alcohol use in Nanjing increased from 332 in 2011 to 428 in 2017，，while the age-standardized death rate attributable to alcohol use decreased from 6.67/105 to 5.96/105. YLLs caused by alcohol use increased from 9090 in 2011 to 11260 in 2017；while the age-standardized YLL rate attributable to alcohol use decreased from 183.66/105 in 2017 to 166.30/105 in 2017. In 2017 both the highest burden of malignant tumor and the highest age-standardized death rate attributed to alcohol use were colon and rectal cancer. After removal of the effects of alcohol use，the life expectancy of Nanjing population aged 20 years and older in 2017 would have reached 63.09 years with an average increase of 0.11 years：0.19 years for man and 0.01 years for women. ［Conclusion］ Alcohol use appears to be an important risk factor for mortality and life expectancy loss among Nanjing residents. Programs related to cancer prevention and control targeting to alcohol use should be strengthened. |
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