| 王 静,袁浩冉,丁高恒,等.2018年甘肃省肿瘤登记地区食管癌流行特征及2010—2018年变化趋势分析[J].中国肿瘤,2022,31(10):774-781. |
| 2018年甘肃省肿瘤登记地区食管癌流行特征及2010—2018年变化趋势分析 |
| Incidence and Mortality of Esophageal Cancer in Cancer Registration Areas of Gansu Province in 2018 and Its Trend from 2010 to 2018 |
| 投稿时间：2022-05-16 |
| DOI：10.11735/j.issn.1004-0242.2022.09.A003 |
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| 中文关键词: 食管癌 发病率 死亡率 趋势 甘肃 |
| 英文关键词:esophageal cancer incidence mortality trend Gansu |
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| 中文摘要: |
| 摘 要：［目的］ 分析甘肃省2018年肿瘤登记地区食管癌流行特征及2010—2018年变化趋势。［方法］ 按照国家癌症中心制定的数据质量审核评价标准，收集整理甘肃省经质量控制合格的15个肿瘤登记点上报的食管癌发病、死亡和人口数据进行汇总分析。按性别、城乡和年龄组分层计算食管癌发病（死亡）率、年龄别发病（死亡）率、标化发病（死亡）率、0～74岁累积发病（死亡）率等。利用Joinpoint线性回归模型分析计算2010—2018年甘肃省肿瘤登记地区食管癌发病（死亡）率的年度变化百分比(APC)。中标率和世标率分别采用2000年中国人口普查标准人口年龄构成和Segi’s世界标准人口年龄构成进行标化。［结果］ 甘肃省肿瘤登记地区2018年新发食管癌病例975例，占全部恶性肿瘤新发病例的7.17%，发病率为18.15/10万，发病中标率为13.12/10万，发病世标率为14.93/10万，累积发病率（0～74岁）为1.81%；肿瘤登记地区食管癌死亡病例608例，占全部恶性肿瘤死亡病例的8.03%，死亡率为11.32/10万，死亡中标率为8.16/10万，死亡世标率为9.57/10万，累积死亡率（0～74岁）为0.95%。2010—2018年甘肃省肿瘤登记地区食管癌发病和死亡呈明显下降趋势，发病中标率APC为-8.60%(P<0.05)，死亡中标率APC为-10.2%(P<0.05)。［结论］ 甘肃省食管癌的整体发病和死亡水平呈下降趋势，但仍为甘肃省负担较重的恶性肿瘤之一，在现有的防控措施基础上应更加针对性地做好高危人群的预防工作，以降低甘肃省食管癌的疾病负担。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the epidemiological characteristics of esophageal cancer in cancer registration areas in Gansu Province in 2018 and the trend from 2010 to 2018. ［Methods］ According to the data quality review and evaluation standards formulated by the National Cancer Center， the esophageal cancer incidence， mortality and population data reported by 15 quality-controlled cancer registries in Gansu Province were collected and analyzed. The incidence(mortality) rate， age-specific incidence(mortality) rate， age-standardized incidence(mortality) rate， cumulative rate(0~74 years old) were calculated by gender， urban and rural areas and age groups. Joinpoint linear regression model was used to analyze and calculate the annual percentage change(APC) of the incidence and mortality of esophageal cancer from 2010 to 2018. The age-standardized rate was adjusted by Chinese standard population in 2000(ASIRC， ASMRC) and world standard(Segi’s) population(ASIRW， ASMRW)， respectively. ［Results］ In 2018， there were 975 new cases of esophageal cancer in the cancer registration areas of Gansu Province， accounting for 7.17% of all new cases of malignant tumors， the crude incidence was 18.15/105， ASIRC and ASIRW were 13.12/105 and 14.93/105， respectively， and cumulative incidence rate(0～74 years old) was 1.81%. There were 608 cases of esophageal cancer death in the cancer registration areas， accounting for 8.03% of all malignant tumor deaths， the mortality rate was 11.32/105， ASMRC and ASMRW were 8.16/105 and 9.57/105， respectively， and the cumulative mortality rate(0～74 years old) was 0.95%. From 2010 to 2018， the incidence and mortality of esophageal cancer in the cancer registration areas of Gansu Province showed significant downward trends， with an APC of -8.60%(P<0.05) and -10.2%(P<0.05)， respectively. ［Conclusion］ The overall incidence and mortality of esophageal cancer show downward trends， but it is still one of the malignant tumors with a heavy burden in Gansu Province. Based on existing prevention and control measures， more targeted prevention work should be done among high-risk groups to decrease the disease burden of esophageal cancer in Gansu Province. |
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