| 孟 娜,罗鹏飞,陆赛博,等.2009—2021年江苏省淮河流域早诊早治项目食管癌筛查结果分析[J].中国肿瘤,2023,32(2):81-88. |
| 2009—2021年江苏省淮河流域早诊早治项目食管癌筛查结果分析 |
| Screening Results of Early Diagnosis and Treatment of Esophageal Cancer in Huaihe River Basin of Jiangsu Province， 2009—2021 |
| 投稿时间：2022-08-13 |
| DOI：10.11735/j.issn.1004-0242.2023.02.A001 |
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| 中文关键词: 食管癌 淮河流域 筛查 江苏 |
| 英文关键词:esophageal cancer Huaihe River basin screening Jiangsu |
| 基金项目:中国消化道早癌医师共同成长计划科研项目（GTCZ-2020-JS-32-0002） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2009—2021年江苏省淮河流域早诊早治项目地区食管癌高危人群内镜筛查情况。［方法］ 采取整群抽样的方法，选取淮安市洪泽区、金湖县、涟水县，盐城市盐都区40~69岁常住居民进行患癌风险评估，对评估出的高危人群进行内镜下碘染色和必要性病理活检。［结果］ 2009—2021年项目评估出高危人群120 901人，其中54 712人完成内镜筛查，筛查率为45.25%（54 712/120 901）；2009—2021年筛查率整体呈上升趋势（χ2趋势=52.634，P＜0.001)。19 046人参与临床病理活检，活检率为34.81%（19 046/54 712）。检出食管癌前病变1 246例，检出率2.28%（1 246/54 712），阳性病变530例，检出率0.97%（530/54 712），早期病例440例，早诊率83.02%（440/530）。随着时间变化，癌前病变及阳性病变检出率整体呈下降趋势（P＜0.001），早诊率呈先降后升趋势（P＜0.001）。 ［结论］ 江苏省淮河流域食管癌早诊早治工作已取得一定的成效，但还应精准评估食管癌高危人群，有效实施临床筛查，及时发现食管病变，进一步提高项目筛查效果。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the endoscopic screening results of the high-risk population of esophageal cancer in Huaihe River basin of Jiangsu Province from 2009 to 2021. ［Methods］ Cluster sampling method was adopted to select residents aged 40~69 years old from Hongze District, Jinhu County, Lianshui County and Yandu District for cancer risk assessment, and endoscopic iodine staining and biopsy were performed on the identified high-risk subjects. ［Results］ From 2009 to 2021, 120 901 people underwent the risk assessment for esophageal cancer， 54 712 people participated in esophageal endoscopy examination with a screening rate of 45.25%(54 712/120 901). With the change of years， there was an overall increasing trend in screening rate(χ2trend=52.634， P<0.001). And 19 046 individuals underwent pathological examination with a pathological examination rate of 34.81%(19 046/54 712). By endoscopy and pathological diagnosis， 1 246 cases were diagnosed as esophageal precancerous lesions(mild or moderate dysplasia)(2.28%) and 530 cases were diagnosed as positive lesions(high-grade dysplasia， carcinoma in situ and esophageal cancer)(0.97%)， among whom 440 cases were in early stage(high-grade dysplasia & carcinoma in situ， early esophageal cancer) with an early diagnosis rate of 83.02%(440/530). With the change of time， the detection rate of precancerous lesions and positive lesions showed a downward trend(P<0.001)， and the early stage diagnosis rate showed an upward trend followed by a downward trend. ［Conclusion］ The early diagnosis and treatment of esophageal cancer in Huaihe River basin of Jiangsu Province has achieved certain progress， but it is still necessary to accurately assess the high-risk group of esophageal cancer， effectively implement clinical screening， timely detect esophageal lesions， and further improve the screening effect of the project. |
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