| 古扎努尔·尼牙孜,袁浩冉,丁高恒,等.2018年甘肃省肿瘤登记地区肺癌流行特征及2010—2018年变化趋势[J].中国肿瘤,2023,32(2):111-117. |
| 2018年甘肃省肿瘤登记地区肺癌流行特征及2010—2018年变化趋势 |
| Incidence and Mortality of Lung Cancer in Cancer Registration Areas of Gansu Province in 2018 and Trends from 2010 to 2018 |
| 投稿时间：2022-11-20 |
| DOI：10.11735/j.issn.1004-0242.2023.02.A005 |
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| 中文关键词: 肺癌 发病率 死亡率 变化趋势 甘肃 |
| 英文关键词:lung cancer incidence mortality trend Gansu |
| 基金项目:甘肃省重点研发项目（711290010037） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2018年甘肃省肿瘤登记地区肺癌流行现状及变化趋势。［方法］ 按性别、城乡和年龄组分层计算肺癌发病（死亡）率、中国人口标化率（中标率）、世界人口标化率（世标率）及年龄别率等指标，描述2018年肺癌流行特征；利用Joinpoint线性回归模型计算年度变化百分比（APC），分析2010—2018年肺癌年度变化趋势。［结果］ 2018年甘肃省肿瘤登记地区肺癌新发病例数为640例，发病率为30.10/10万，中标率为22.03/10万，世标率为24.87/10万，0~74岁累积率为2.74%；肺癌死亡病例数为515例，死亡率为24.22/10万，中标率为18.18/10万，世标率为21.03/10万，0~74岁累积率为2.18%；农村发病率为城市的1.61倍，死亡率是城市的1.91倍；肺癌男性年龄别发病率和死亡率分别在80~84岁和75~79岁年龄组达到最高峰，女性在75~79岁和85岁及以上年龄组达到最高峰；肺癌发病和死亡情况地区分布情况显示，景泰县发病率和死亡率均为最高，武威市凉州区均为最低。2010—2018年甘肃省肿瘤登记地区肺癌中标发病率APC为0.60%（95%CI：-1.31%~2.55%），中标死亡率APC为4.80%（95%CI：-2.23%~12.35%），变化趋势差异均无统计学意义（P>0.05）。［结论］ 甘肃省肺癌发病及死亡率虽低于全国平均水平，但仍属于甘肃省高发癌种，已严重威胁居民生命健康，应积极推进肺癌高危人群评估及筛查早诊早治工作，有效遏制肺癌的高发态势。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of lung cancer in cancer registration areas in Gansu Province in 2018 and its changing trend from 2010 to 2018. ［Methods］ The epidemiological characteristics of lung cancer in 2018 was described by calculating the incidence and mortality rate of lung cancer， the age-standardized rate of the Chinese population(ASIRC， ASMRC)， the age-standardized rate of the world population(ASIRW， ASMRW)， and the cumulative rate and other indicators. The annual percentage change(APC) was calculated by the Joinpoint Regression Software， to analyze the trend of lung cancer from 2010 to 2018. ［Results］ In 2018， there were 640 new cases of lung cancer in the cancer registration area of Gansu Province， the crude incidence was 30.10/105； ASIRC and ASIRW were 22.03/105 and 24.87/105， respectively， and the cumulative rate (0~74 years old） was 2.74%. There were 515 deaths from lung cancer， with a crude mortality rate of 24.22/105； ASMRC and ASMRW were 18.18/105 and 21.03/105， respectively， and the cumulative rate (0~74 years old） was 2.18%. The incidence rate in rural areas was 1.61 times of that in urban areas， and the mortality rate was 1.91 times of that in urban areas. The age-specific incidence and mortality rates of lung cancer in male reached the peaks at 80~84 age group and 75~79 age group， and in female at 75~84 age group and 85+ age group. Jingtai County had the highest lung cancer incidence and mortality， and Liangzhou District had the lowest among all regions in the province. From 2010 to 2018， the APC of ASIRC of lung cancer in Gansu Province was 0.60% (95%CI： -1.31%~2.55%， P>0.05)， and the APC of ASMRC was 4.80%(95%CI： -2.23%~12.35%， P>0.05). ［Conclusion］ Although the incidence and mortality of lung cancer in Gansu Province are lower than the national average level， but the incidence and mortality are increasing year by year， which has seriously threatened the life and health of residents in the province. |
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