| 闫 超,陕 飞,李子禹.2020年全球胃癌负担分析：聚焦中国流行现状[J].中国肿瘤,2023,32(3):161-170. |
| 2020年全球胃癌负担分析：聚焦中国流行现状 |
| Analysis of Global Burden of Gastric Cancer in 2020： Focusing on the Statistics in China |
| 投稿时间：2022-12-16 |
| DOI：10.11735/j.issn.1004-0242.2023.03.A001 |
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| 中文关键词: 胃癌 疾病负担 发病率 死亡率 全球 中国 |
| 英文关键词:gastric cancer disease burden incidence mortality worldwide China |
| 基金项目:北京市医院管理中心登峰人才计划（DFL20191103） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2020年中国与全球各地区的胃癌发病及死亡数据，了解胃癌流行情况和疾病负担。［方法］ 以国际癌症研究署发布的GLOBOCAN 2020全球癌症发病率和死亡率估算数据为基础，提取其中各个国家及地区的胃癌年龄标化发病及死亡数据，对比中国与全球20个地区的胃癌发病、死亡情况。［结果］ 2020年全球胃癌新发及死亡病例数分别为1 089 103例和768 793例。东亚地区胃癌新发和死亡病例数最高，分别为651 864例和432 325例。全球男性胃癌年龄标化发病率和死亡率（ASIR和ASMR）均高于女性，分别为女性的2.26及2.23倍，且ASIR和ASMR越高的地区，男女差异越大。胃癌发病率和死亡率在40岁及以上持续升高，新发和死亡病例数在65~岁年龄组达到高峰。各地区的人类发展指数（HDI）水平与ASIR呈弱相关（R2=0.03，P=0.014），与ASMR无相关性（P=0.902）。我国胃癌新发及死亡病例数为478 508例和373 789例，分别占全球的43.94%和48.62%，ASIR和ASMR分别为20.74/10万和15.99/10万，均处于全球较高水平。［结论］ 全球胃癌发病率与HDI弱相关，死亡率与HDI无显著相关性，疾病负担主要集中于东亚地区，特别是中国。中国的胃癌发病率和死亡率均处于全球较高水平，未来仍需加强防控，改善流行现状。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the incidence and mortality data of gastric cancer in China and other regions of the world in 2020. ［Methods］ The age-specific incidence and mortality data of gastric cancer in various regions from GLOBOCAN 2020 published by International Agency for Research on Cancer(IARC) were extracted to make comparison between China and 20 regions in the world. ［Results］ It was estimated that the number of new cases and deaths of gastric cancer in the world were 1 089 103 and 768 793， respectively in 2020. Among the 20 regions， the largest number of new cases and deaths were found in East Asia， which were 651 864 and 432 325. The age-standardized incidence rate(ASIR) and age-standardized mortality rate(ASMR) in male was 2.26 and 2.23-fold higher than those in female， respectively. Furthermore， the sex ratio(male∶female) tended to rise uniformly with increasing ASIR and ASMR. The ASIR and ASMR in all regions of the world continued to increase after the age of 40， and the new cases and deaths peaked at the age group of 65. The correlation between human development index (HDI) and ASIR was weak(R2=0.03， P=0.014) and there was no correlation between HDI and ASMR(P=0.902). The number of new cases and deaths in China were 478 508 and 373 789， accounting for 43.94% and 48.62% of the world respectively. The ASIR and ASMR was 20.74/105 and 15.99/105， both ranking at a high level in the world. ［Conclusion］ There is a week correlation of HDI with global incidence rate of gastric cancer and no significant correlation with mortality rate. The disease burden is mainly concentrated in East Asia， especially in China. Both ASIR and ASMR in China present a high level in the world. The prevention and control of gastric cancer should be strengthened to improve the epidemic situation in the future. |
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