| 李德喜,梁 岭,王华东,等.安徽省淮河流域食管癌高危人群内镜筛查参与率、病变检出率及相关影响因素分析[J].中国肿瘤,2023,32(5):378-386. |
| 安徽省淮河流域食管癌高危人群内镜筛查参与率、病变检出率及相关影响因素分析 |
| Screening of Esophageal Cancer in Huaihe River Basin of Anhui Province, 2013—2018 |
| 投稿时间：2022-09-23 |
| DOI：10.11735/j.issn.1004-0242.2023.05.A007 |
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| 中文关键词: 食管癌 淮河流域 参与率 检出率 影响因素 内镜检查 安徽 筛查 |
| 英文关键词:esophageal cancer Huaihe River basin participation rate detection rate influencing factors endoscopy Anhui screening |
| 基金项目:国家重点研发计划（2016YFC1302605）；安徽省重点研发计划（1704a0802156） |
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| 中文摘要: |
| 摘 要：［目的］ 分析2013—2018年安徽省淮河流域食管癌高危人群的内镜筛查参与率和病变检出情况及其影响因素，为制定有效筛查策略提供依据。［方法］ 2013—2018年间，采用整群抽样方法，对安徽省淮河流域40～69岁常住居民面对面进行健康因素问卷调查和食管癌风险评估，对评估出食管癌高危人群进行临床内镜筛查，比较不同特征对象内镜筛查参与率和病变检出率及其影响因素。［结果］ 2013—2018年共筛查发现食管癌高危人群22 096人，高危率为39.55%（22 096/55 868），内镜筛查参与率为41.23%（9 111/22 096），2018年的高危人群食管癌内镜筛查参与率最低，仅为26.22%，多因素Logistic回归模型分析结果显示：女性、中学及以上、不吸烟、肥胖、胃及十二指肠溃疡史、食管炎病史、胃肠炎病史、癌症家族史等高危人群更愿意参加食管癌内镜筛查（P<0.05）。共检出食管癌及癌前病变174例（1.91%）。多因素Logistic回归分析结果显示：与 40~44岁人群相比，60~64 岁（OR=2.086，95%CI：1.129~3.855）以及 65~69 岁（OR=2.709，95%CI：1.457~5.040）的人群食管癌前病变及癌检出率较高；女性(OR=0.566，95%CI：0.371~0.863)每周食用新鲜水果至少2次（OR=0.591，95%CI：0.428~0.816）的人群更不易检出食管癌及癌前病变。［结论］ 安徽省淮河流域食管癌高危人群内镜筛查参与率和检出率较低，应通过加强健康教育、普及癌症防治知识、倡导健康生活方式等健康促进措施，提高食管癌内镜筛查参与率和检出率，提高筛查效果及防控水平。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the results of esophageal cancer screening in Huaihe River basin of Anhui Province from 2013 to 2018. ［Methods］ A esophageal cancer screening program was conducted among permanent residents aged 40～69 years old in the Huaihe River basin of Anhui Province by using cluster sampling method from 2013 to 2018. A face-to-face health questionnaire survey was conducted for esophageal cancer risk assessment， and the high-risk subjects underwent endoscopic screening. The participation rate， detection rate of esophageal cancer and their influencing factors were analyzed. ［Results］ From 2013 to 2018， a total of 22 096 people were identified as high risk of esophageal cancer with a high risk rate of 39.55%(22 096/55 868)， among whom 9 111 people underwent endoscopic examination with a participation rate of 41.23% and the lowest participation rate(26.22%) in 2018. Multivariate Logistic regression analysis showed that women gender， secondary school or above education， non-smoking， obesity， history of gastric and duodenal ulcer， history of esophagitis， history of gastroenteritis， and family history of cancer were influencing factors for participation in the endoscopic screening(P<0.05). A total of 174 cases(1.91%) of esophageal cancer or precancerous lesions were detected. Multivariate Logistic regression analysis showed that compared to 40～44 years of age， 60～64 years of age(OR=2.086， 95%CI： 1.129～3.855) and 65～69 years of age(OR=2.709， 95%CI： 1.457～5.040) were independent risk factors for detection of esophageal cancer or precancerous lesions; while women sex(OR=0.566， 95%CI 0.371～0.863) and comsumption of fresh fruit at least twice a week(OR=0.591， 95%CI： 0.428～0.816) were protective factors for esophageal cancer or precancerous lesions. ［Conclusion］ The participation rate and detection rate of endoscopic screening among high risk population of esophageal cancer in the Huaihe River basin of Anhui Province are relatively low. Health promotion and health education for cancer prevention and control should be strengthened to improve the participation rate of esophageal cancer screening. |
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