| 陆赛博,罗鹏飞,孟 娜,等.2011—2021年江苏省淮河流域癌症早诊早治项目肝癌筛查情况分析[J].中国肿瘤,2023,32(5):387-393. |
| 2011—2021年江苏省淮河流域癌症早诊早治项目肝癌筛查情况分析 |
| Liver Cancer Screening in Huaihe River Basin of Jiangsu Province from 2011 to 2021 |
| 投稿时间：2022-08-23 |
| DOI：10.11735/j.issn.1004-0242.2023.05.A008 |
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| 中文关键词: 肝癌 筛查 早诊早治 淮河流域 江苏 |
| 英文关键词:liver cancer screening early diagnosis and treatment Huaihe River areas Jiangsu |
| 基金项目:江苏省卫生健康委老年健康科研课题(LKM2022006) |
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| 中文摘要: |
| 摘 要：［目的］评价2011—2021年度江苏省淮河流域癌症早诊早治项目肝癌筛查情况。［方法］在本研究所覆盖的江苏省盐城市（亭湖区、滨海县、射阳县）、淮安市（洪泽区），采用整群抽样方法，选取男性35~64岁及女性45~64岁的居民为研究对象，进行问卷调查，对高危人群进行B超和甲胎蛋白（alpha fetoprotein，AFP）检测，收集问卷调查数据及临床筛查数据，分析各地区肝癌早诊早治项目参与情况及筛查结果。［结果］共248 980人参与问卷调查，其中42 357人为高危人群，高危率为17.01%（42 357/248 980），男性高于女性（P＜0.05）。高危人群中参与临床筛查28 193人，筛查率为66.56%（28 193/42 357），女性高于男性（P＜0.05）。随着年龄的增长，高危率及筛查率增加。在高危且参与临床筛查人群中共检出430例阳性病例，检出率为1.53%（430/28 193）；AFP阳性358例，检出率为1.27%（358/28 193）；可疑肝癌40例，检出率0.14%（40/28 193）；肝癌56例，检出率0.20%（56/28 193）。各项目点高危率、筛查率及筛查阳性检出率差异有统计学意义（P＜0.05）。［结论］江苏省淮河流域肝癌总体筛查率较高，但检出率偏低，需进一步加强防治肝癌健康知识宣教，采用更高效的筛查手段，增加男性及55~64岁年龄组的筛查，以提高阳性病变检出率。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the results of liver cancer screening in Huaihe River basin in Jiangsu Province from 2011 to 2021. ［Methods］ The liver cancer screening program was conducted among residents aged 35~64 years old for males and 45～64 years old for females selected by cluster sampling in Yancheng and Huai’an of Jiangsu province during 2011 to 2012. The screening protocol included questionnaire survey for risk assessment， and clinical screening(ultrasonography and blood AFP test) for high-risk groups. The screening results were analyzed. ［Results］ A total of 248 980 residents participated in the questionnaire survey for risk assessment from 2011 to 2021， among whom 42 357 were identified as high-risk group with a high-risk rate of 17.01%， and the high-risk rate in male was higher than that in female(P<0.05). A total of 28 193 subjects from high-risk population participated in clinical screening with a screening rate of 66.56%(28 193/42 357)， the participation rate in female was higher than that in male(P<0.05). The risk and screening rates increased with age. A total of 430 positive cases were detected in the clinical screening with a detection rate of 1.53%(430/28 193)， there were 358 cases of positive AFP test with a positive rate of 1.27%(358/28 193). Fifty-six cases of hepatocellular carcinoma were detected with a detection rate of 0.20%(56/28 193) and 40 cases of suspected liver cancer were detected with a detection rate of 0.14%(40/28 193). There were significant differences in high risk rate， screening rate and positive detection rate among project sites(P<0.05). ［Conclusion］ Although the participation rate of clinical screening for Huaihe River basin in Jiangsu Province is high， but the detection rate is relatively low. It is necessary to further to strengthen the publicity of health knowledge on the prevention and control of liver cancer to improve the efficiency of liver cancer screening. |
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