| 李道娟,刘言玉,贺宇彤,等.2018年河北省肿瘤登记地区上消化道癌流行现状及1988—2018年高发区流行特征变化趋势[J].中国肿瘤,2023,32(6):407-413. |
| 2018年河北省肿瘤登记地区上消化道癌流行现状及1988—2018年高发区流行特征变化趋势 |
| Incidence and Mortality of Upper Gastrointestinal Cancer in Cancer Registration Areas of Hebei Province in 2018 and the Trends in High Risk Areas from 1988 to 2018 |
| 投稿时间：2023-02-15 |
| DOI：10.11735/j.issn.1004-0242.2023.06.A002 |
|
 |
| 中文关键词: 上消化道癌 肿瘤登记 流行趋势 河北 |
| 英文关键词:upper gastrointestinal cancer cancer registration epidemiology trend Hebei |
| 基金项目:河北省自然科学基金京津冀联合基金项目（H2020206644） |
|
| 摘要点击次数: 461 |
| 全文下载次数: 112 |
| 中文摘要: |
| 摘 要：［目的］ 分析2018年河北省肿瘤登记地区上消化道癌流行现状及1988—2018年上消化道癌高发区发病与死亡趋势变化。［方法］ 收集、整理质控合格的2018年河北省上消化道癌发病和死亡数据，分别计算不同地区、性别、年龄别的粗发病率、粗死亡率、世标发病率、世标死亡率和构成比等指标，统计食管癌和胃癌的亚部位及病理类型。分析1988—2018年磁县和涉县高发区上消化道癌发病和死亡特征及时间趋势变化。［结果］ 2018年河北省肿瘤登记地区上消化道癌的粗发病率为46.26/10万，粗死亡率为37.35/10万。2018年食管癌年龄别发病率和死亡率均在80~84岁组达到高峰；胃癌年龄别发病率在70~74岁组达到高峰，年龄别死亡率在85岁及以上组达到高峰。食管癌病例有明确的亚部位信息占43.70%，其中，50.85%的病例发生在食管中1/3；食管癌病例有病理学诊断信息的病例占70.78%，其中鳞癌是最主要的病理类型，占87.93%。胃癌病例有明确亚部位信息的占50.32%，其中57.90%发生在贲门；胃癌病例有病理学诊断信息的病例占66.23%，其中腺癌是最主要的病理类型，占90.64%。1988—2018年磁县食管癌世标发病率和死亡率均呈明显下降趋势（P值均<0.01），胃癌世标发病率变化呈略微上升状态（P<0.01），世标死亡率趋势变化不明显（P=0.10）。2000—2018年涉县食管癌和胃癌世标发病率、世标死亡率均呈明显下降趋势（P值均<0.01）。［结论］ 经过综合防治，有效降低了河北省上消化道癌的发病率和死亡率，但仍需继续加强河北省上消化道癌的三级预防。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the incidence and mortality of upper gastrointestinal cancer in cancer registration areas of Hebei Province in 2018 and the trends in high-risk areas from 1988 to 2018. ［Methods］ The incidence and mortality data of upper gastrointestinal cancer in Hebei Province in 2018 were collected from cancer registries. The incidence rate， mortality rate， age-standardized incidence rate by world standard population(ASIRW)， age-standardized mortality rate by world standard population(ASMRW) and constituent ratio by regions， genders and ages were calculated. The locations and pathological types of esophageal cancer and gastric cancer were stratified. The characteristics and time trend of upper gastrointestinal cancer in Cixian and Shexian high-incidence areas were analyzed. ［Results］ The crude incidence rate of upper gastrointestinal cancer in the cancer registration area of Hebei Province in 2018 was 46.26/105， and the crude mortality rate was 37.35/105. The age-specific incidence and mortality of esophageal cancer reached the peak at the age group of 80~84 years. The age-specific incidence and mortality of gastric cancer peaked at the age groups of 70~74 and 85+ years， respectively. Information of location were available in 43.70% of esophageal cancer patients， among whom 50.85% occurred in middle one third of the esophagus； pathological diagnosis was confirmed in 70.78% of patients， among whom squamous cell carcinoma was the main pathological type， accounting for 87.93%. Information of location were available in 50.32% of gastric cancer patients， among whom 57.90% occurred in the cardia； pathological diagnosis was confirmed in 66.23% of patients， among whom adenocarcinoma was the main pathological type， accounting for 90.64%. From 1988 to 2018， ASIRW and ASMRW of esophageal cancer in Cixian showed a significant decrease(both P<0.01)， the ASIRW of gastric cancer increased slightly(P<0.01)， and the trend of ASMRW was not significant(P=0.10). From 2000 to 2018， the ASIRW and ASMRW of esophageal cancer and gastric cancer in Shexian showed a significant decreasing trend(both P<0.01). ［Conclusion］ The incidence and mortality rate of upper gastrointestinal cancer in Hebei Province had been effectively reduced， but the tertiary prevention of upper gastrointestinal cancer still need to be strengthened. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |