| 张 敏,杨晓明,高文君,等.2005—2018年上海市静安区恶性肿瘤发病和死亡趋势分析[J].中国肿瘤,2023,32(12):907-916. |
| 2005—2018年上海市静安区恶性肿瘤发病和死亡趋势分析 |
| Trends of Incidence and Mortality of Malignant Tumors in Jing’an District of Shanghai， 2005—2018 |
| 投稿时间：2023-06-06 |
| DOI：10.11735/j.issn.1004-0242.2023.12.A004 |
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| 中文关键词: 恶性肿瘤 发病率 死亡率 趋势 上海 |
| 英文关键词:malignant tumors incidence mortality trend Shanghai |
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| 中文摘要: |
| 摘 要：［目的］ 分析2005—2018年上海市静安区恶性肿瘤流行及变化趋势。［方法］ 根据静安区恶性肿瘤发病和死亡情况结合人口学资料，分别计算发病和死亡率、世标率（Segi世界标准人口年龄构成）、中标率（2000年中国标准人口构成）及不同年份的年龄别率及顺位指标，运用Joinpoint模型计算年度变化百分比（annual percentage change，APC）及平均年度变化百分比（average annual percentage change，AAPC），分析肿瘤发病和死亡变化趋势。［结果］ 2005—2018年静安区恶性肿瘤平均发病率为496.70/10万，世标率221.28/10万，中标率229.59/10万，60岁以后发病率快速上升。肺癌、结直肠癌、乳腺癌、甲状腺癌和胃癌是近年来的主要发病癌种，且发病世标率和中标率均呈上升趋势（AAPC分别为2.29%和2.48%）。恶性肿瘤死亡率为284.05/10万，世标率102.27/10万，中标率103.48/10万，65岁以后死亡率快速上升。肺癌、结直肠癌、胃癌、肝癌、胰腺癌是近年来的主要死亡癌种，死亡世标率和中标率均呈下降趋势（APC分别为-1.82%和-1.94%）。［结论］ 肺癌、消化系统恶性肿瘤（结直肠癌、胃癌）及女性乳腺癌仍是威胁上海市静安区居民生命健康的主要恶性肿瘤，且老年人群是肿瘤防治重点干预群体。应通过控烟、人群筛查等手段控制发病率持续上升，努力维持死亡率逐年下降。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the trends of incidence and mortality of malignant tumor in Jing’an District of Shanghai from 2005 to 2018. ［Methods］ The data of cancer new cases and deaths， as well as the population data from 2005 to 2018 in Jing’an District were collected. The crude incidence and mortality rates were calculated. Segi world population and Chinese population census in 2000 were used for age-standardized rate (ASRW and ASRC). Age-specific rate and ranks of main tumors in different years were analyzed. The annual percentage change(APC) and average annual percentage change (AAPC) were calculated by Joinpoint model to analyze the trends of cancer incidence and mortality. ［Results］ From 2005 to 2018 the crude cancer incidence rate in Jing’an District was 496.70/105， age-standardized incidence rate by Segi’s world population (ASIRW) was 221.28/105， age-standardized rate by Chinese standard population in 2000 (ASIRC) was 229.59/105， and the incidence increased rapidly after the age of 60 years old. In addition， the top five malignant tumors were lung， colorectal， breast， thyroid and stomach cancers. The AAPC of ASRW and ASRC of incidence from 2005 to 2018 was 2.29% and 2.48%， respectively. The crude cancer mortality rate was 284.05/105， ASMRW was 102.27/105， ASMRC was 103.48/105， and the mortality rate increased rapidly after the age of 65 years old. The top five malignant tumors in death were lung， colorectal， stomach， liver and pancreatic cancers. The APC of ASRW and ASRC of mortality from 2005 to 2018 was -1.82% and -1.94%， respectively. ［Conclusion］ Lung， colorectal， stomach and female breast cancers are still the main threatening of the health of residents in Jing’an District， efforts should be made to keep the incidence and mortality of malignant tumors decreasing constantly. |
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