| 于昕辉,王黎君,殷 鹏,等.基于GBD数据分析1990年和2019年中国恶性肿瘤疾病负担性别差异[J].中国肿瘤,2024,33(1):27-35. |
| 基于GBD数据分析1990年和2019年中国恶性肿瘤疾病负担性别差异 |
| Gender Differences of Cancer Disease Burden in China Based on GBD Data in 1990 and 2019 |
| 投稿时间：2023-11-12 |
| DOI：10.11735/j.issn.1004-0242.2024.01.A005 |
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| 中文关键词: 恶性肿瘤 疾病负担 性别差异 中国 |
| 英文关键词:cancer disease burden gender difference China |
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| 摘要点击次数: 180 |
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| 中文摘要: |
| 摘 要：［目的］ 分析2019年中国男性和女性常见恶性肿瘤的疾病负担情况，并探讨1990年和2019年我国不同省（区、市）常见恶性肿瘤发病与死亡的性别差异及其变化。［方法］ 利用2019年全球疾病负担研究中国数据，分析常见恶性肿瘤的发病率、标化发病率、死亡率、标化死亡率和伤残调整寿命年（disability-adjusted life years，DALY）率指标，计算相应指标的男女性别比（男性比女性）及95%置信区间（CI）。［结果］ 2019年中国男、女性常见恶性肿瘤发病率性别比为1.54（95%CI：1.49~1.60），死亡率性别比为1.88（95%CI：1.82~1.95）。男、女性常见肿瘤标化发病率性别比为1.71（95%CI：1.65~1.77），标化死亡率性别比为2.20（95%CI：2.13~2.27）。男、女性常见恶性肿瘤DALY率性别比为1.96（95%CI：1.89~2.02）。与1990年相比，2019年常见肿瘤发病率性别比在吉林省、西藏自治区和新疆维吾尔自治区下降明显，死亡率性别比仅在吉林省、天津市、新疆维吾尔自治区和黑龙江省降低，湖南省、四川省和安徽省的发病率和死亡率性别差异均明显增大（P<0.05）。［结论］ 中国常见恶性肿瘤发病与死亡水平仍存在显著性别差异，部分地区恶性肿瘤的发病、死亡性别差异扩大。根据不同类型肿瘤的性别差异特征，对不同地区和人群有针对性地进行卫生健康知识宣教，合理分配卫生资源，加强肿瘤预防和早诊早治，有利于减轻恶性肿瘤所带来的疾病负担。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the burden of disease of cancers between male and female in China in 2019， and to explore the gender difference and changes of the incidence and death of common cancers in different provinces (autonomous regions and municipalities) in 1990 and 2019. ［Methods］ Using the Chinese data of the Global Burden of Disease Study 2019， the incidence， standardized incidence， mortality， standardized mortality and disability-adjusted life years (DALY) rates were analyzed， calculating the gender ratio (male to female) and 95% confidence interval (CI). ［Results］ In 2019， the gender ratio of the incidence of common cancers in China was 1.54 (95%CI： 1.49~1.60)， and the gender ratio of the mortality rate was 1.88 (95%CI： 1.82~1.95). The gender ratio of standardized incidence was 1.71 (95%CI： 1.65~1.77)， and the gender ratio of standardized mortality was 2.20 (95%CI： 2.13~2.27). The gender ratio of DALY rate in common cancers between male and female was 1.96 (95%CI： 1.89~2.02). Compared with 1990， the gender ratio of incidence rate in 2019 decreased significantly in Jilin， Xizang and Xinjiang， the gender ratio of mortality rate decreased only in Jilin， Tianjin， Xinjiang and Heilongjiang， and the gender differences in incidence rate and mortality rate in Hunan， Sichuan and Anhui were significantly larger(P<0.05). ［Conclusion］ There are still large gender differences in the incidence and death of common cancers in China， and gender differences in the incidence and death of malignant cancers have widened in some regions. According to the gender-specific characteristics of different types of cancers， targeted health education for different regions and groups of people， the rational allocation of health resources， and the strengthening of cancer prevention and early diagnosis and treatment are conducive to reducing the social burden caused by cancers. |
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