| 由金玲,徐晓慧,林 琳,等.基于GBD数据分析1990年和2019年中国人群癌谱差异[J].中国肿瘤,2024,33(1):36-43. |
| 基于GBD数据分析1990年和2019年中国人群癌谱差异 |
| Analysis of Cancer Spectrum in China Based on GBD Data in 1990 and 2019 |
| 投稿时间：2023-11-11 |
| DOI：10.11735/j.issn.1004-0242.2024.01.A006 |
|
 |
| 中文关键词: 癌谱 恶性肿瘤 发病 死亡 顺位 中国 |
| 英文关键词:cancer spectrum malignant tumors incidence mortality rank China |
| 基金项目: |
|
| 摘要点击次数: 153 |
| 全文下载次数: 104 |
| 中文摘要: |
| 摘 要：［目的］ 分析中国1990年和2019年恶性肿瘤发病和死亡顺位的年龄、性别和时空特点差异。［方法］ 利用全球疾病负担研究（Global Burden of Disease，GBD）数据，对我国1990年和2019年不同性别、年龄组、地区人群恶性肿瘤的发病和死亡顺位进行分析比较。采用整体建模策略估计恶性肿瘤死亡数和死亡率，通过死亡发病比估算发病数和发病率。以发病率或死亡率确定各类恶性肿瘤发病或死亡顺位。［结果］ 2019年中国居民发病率前5位的恶性肿瘤依次为肺癌、胃癌、结直肠癌、乳腺癌、非黑色素瘤皮肤癌，其中男性发病率前5位的恶性肿瘤依次为肺癌、胃癌、结直肠癌、食管癌、肝癌，共占男性恶性肿瘤总发病的62.42%；女性发病率前5位的恶性肿瘤依次为乳腺癌、肺癌、结直肠癌、胃癌、非黑色素瘤皮肤癌，共占女性恶性肿瘤总发病的59.82%。2019年中国居民死亡率前5位的恶性肿瘤依次为胃癌、肺癌、肝癌、食管癌、结直肠癌，其中男性死亡率前5位的恶性肿瘤依次为肺癌、胃癌、食管癌、结直肠癌、肝癌，占男性恶性肿瘤总死亡的75.65%；女性死亡率前5位的恶性肿瘤依次为肺癌、胃癌、结直肠癌、乳腺癌、食管癌，共占女性恶性肿瘤总死亡的51.17%。白血病居2019年中国0~14岁年龄组恶性肿瘤发病和死亡首位，肺癌居50岁及以上年龄段恶性肿瘤发病与死亡首位。各省（区、市）癌谱顺位不同。与1990年相比，2019年发病前10位的恶性肿瘤中顺位上升的为肺癌、结直肠癌、乳腺癌、非黑色素瘤皮肤癌、前列腺癌；死亡前10位中位次上升的为肺癌、结直肠癌、胰腺癌、前列腺癌。［结论］ 中国癌谱性别、年龄、地区、时间差异明显，呈现发达国家和发展中国家兼有的特点，应针对不同特征人群采取不同的恶性肿瘤防治措施。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the ranking changes of cancer incidence and mortality by age， gender， time and geographic regions in China in 1990 and 2019. ［Methods］ The Global Burden of Disease (GBD) 2019 data was used to analyze the ranking changes of mortality and incidence of malignant tumors by gender， age， time and region in China in 1990 and 2019. An overall modeling strategy was used to estimate the number of deaths and mortality rate， and the incidence and incidence rate were estimated by the mortality to incidence ratio. ［Results］ In 2019， the top 5 malignant tumors of high incidence in China were lung cancer， stomach cancer， colorectal cancer， breast cancer and non-melanoma skin cancer； for males those were lung cancer， stomach cancer， colorectal cancer， esophageal cancer and liver cancer， accounting for 62.42% of all malignant tumors in male； while for females those were breast cancer， lung cancer， colorectal cancer， stomach cancer and non-melanoma skin cancer， accounting for 59.82% of all malignant tumors in female. In 2019， the top 5 malignant tumors of high mortality in China were stomach cancer， lung cancer， liver cancer， esophageal cancer and colorectal cancer； for males those were lung cancer， stomach cancer， esophageal cancer， colorectal cancer and liver cancer， accounting for 75.65% of all male cancer deaths； while for females those were lung cancer， stomach cancer， colorectal cancer， breast cancer and esophageal cancer， accounting for 51.17% of all female can cer deaths. Leukemia ranked first in the incidence and death of malignant tumors in the age group of 0~14 in 2019， and lung cancer ranked first in the incidence and death of malignant tumors aged 50 and above. Cancer spectrum varied in different provinces (regions and municipalities). Compared with 1990， lung cancer， colorectal cancer， breast cancer， non-melanoma skin cancer and prostate cancer rose up their ranks in the top 10 malignant tumors of high incidence in 2019； lung cancer， colorectal cancer， pancreatic cancer and prostate cancer rose up their ranks in the top 10 malignant tumors of high mortality in 2019. ［Conclusion］ The cancer ranking in China shows significant changes by gender， age groups， regions， and time， presenting both characteristics of developed and developing countries. Different cancer prevention and control measures should be taken for populations with different characteristics accordingly. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |