| 蒋永俊,吴俣婷,丁高恒,等.2019年甘肃省肿瘤登记地区结直肠癌流行特征及2010—2019年变化趋势分析[J].中国肿瘤,2024,33(2):87-95. |
| 2019年甘肃省肿瘤登记地区结直肠癌流行特征及2010—2019年变化趋势分析 |
| Epidemiological Characteristics of Colorectal Cancer in Cancer Registration Areas of Gansu Province in 2019 and Trend from 2010 to 2019 |
| 投稿时间：2023-07-31 |
| DOI：10.11735/j.issn.1004-0242.2024.02.A002 |
|
 |
| 中文关键词: 结直肠癌 发病率 死亡率 疾病负担 甘肃 |
| 英文关键词:colorectal cancer incidence mortality burden of disease Gansu |
| 基金项目:甘肃省卫生健康行业科研计划（GSWSKY2022-80） |
|
| 摘要点击次数: 172 |
| 全文下载次数: 87 |
| 中文摘要: |
| 摘 要：［目的］ 分析2019年甘肃省肿瘤登记地区结直肠癌流行特征及2010—2019年变化趋势。［方法］ 收集2019年甘肃省23个肿瘤登记点的结直肠癌登记数据，覆盖人口为9 272 055人，分别计算发病（死亡）率、年龄标化率、伤残调整寿命年（DALY)等相关指标；采用Joinpoint线性回归模型计算平均年度变化百分比（AAPC)。［结果］ 2019年甘肃省肿瘤登记地区结直肠癌发病率为23.90/10万（男性为26.48/10万，女性为21.22/10万），中标发病率、世标发病率分别为15.56/10万和15.34/10万，0~74岁累积发病率为1.90%；结直肠癌死亡率为9.22/10万（男性为9.83/10万，女性为8.59/10万），中标死亡率、世标死亡率分别为5.69/10万、5.58/10万，0~74岁累积死亡率为0.60%。发病率和死亡率高峰分别在75~79岁组和80~84岁组。结直肠癌发病率和死亡率最高的地区分别为兰州市城关区和敦煌市，最低均为兰州市红古区。2010—2019年甘肃省肿瘤登记地区总DALY率由2010年的2.7/千人年上升到2019年的4.0/千人年。2010—2019年甘肃结直肠癌中标发病率AAPC为21.13%(95%CI：16.16%~26.31%)，差异有统计学意义（P<0.05），中标死亡率AAPC为-6.29%（95%CI：-15.43%~3.84%），差异无统计学意义（P>0.05）。［结论］ 2019年甘肃省结直肠癌发病率和死亡率均低于全国平均水平, 但2010—2019年结直肠癌发病率和疾病负担仍呈上升趋势。 |
| 英文摘要: |
| Abstract： ［Purpose］ To analyze the epidemiological characteristics of colorectal cancer in cancer registration areas of Gansu Province in 2019 and the change trend from 2010 to 2019. ［Methods］ Colorectal cancer data in Gansu Province in 2019 were collected from 23 cancer registration areas covering a population of 9 272 055. The incidence/mortality rate， age-standardized rate， disability-adjusted life years (DALY) and other related indicators were calculated. The Joinpoint linear regression model was used to calculate the average annual percentage change (AAPC). ［Results］ The crude incidence of colorectal cancer in 2019 was 23.90/105(26.48/105 in male and 21.22/105 in female)； the age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 15.56/105 and 15.34/105， respectively； the cumulative incidence (0~74 years old) was 1.90% . The crude mortality rate of colorectal cancer in 2019 was 9.22/105 (9.83/105 in male and 8.59/105 in female)； the age-standardized mortality rate by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 5.69/105 and 5.58/105， respectively； the cumulative mortality rate (0~74 years old) was 0.60%. The peak of crude incidence rate and crude mortality rate were in age groups of 75~79 years old and 80~84 years old， respectively. The highest incidence rate and mortality rate of colorectal cancer were in Chengguan District of Lanzhou City and Dunhuang City， and the lowest were in Honggu District of Lanzhou City. The total DALY rate in cancer registration areas of Gansu Province increased from 2.7 per 1 000 person years in 2010 to 4.0 per 1 000 person years in 2019. The AAPC of ASIRC of colorectal cancer from 2010 to 2019 was 21.13% (95%CI： 16.16%~26.31%， P<0.05)，The AAPC of ASMRC from 2010 to 2019 was -6.29%(95%CI：-15.43%~3.84%)(P>0.05). ［Conclusion］ The incidence and mortality rates of colorectal cancer in Gansu Province are both lower than the national level in 2019， but there are increasing trends both for incidence rate and disease burden of colorectal cancer from 2010 to 2019. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |