| 吴俣婷,蒋永俊,丁高恒,等.2019年甘肃省肿瘤登记地区宫颈癌流行特征及2010—2019年变化趋势分析[J].中国肿瘤,2024,33(2):103-110. |
| 2019年甘肃省肿瘤登记地区宫颈癌流行特征及2010—2019年变化趋势分析 |
| Epidemiological Characteristics of Cervical Cancer in Cancer Registration Areas of Gansu Province in 2019 and Trend from 2010 to 2019 |
| 投稿时间：2023-07-20 |
| DOI：10.11735/j.issn.1004-0242.2024.02.A004 |
|
 |
| 中文关键词: 宫颈癌 发病率 死亡率 疾病负担 甘肃 |
| 英文关键词:cervical cancer incidence mortality disease burden Gansu |
| 基金项目:甘肃省卫生健康行业科研计划（GSWSKY2022-80） |
|
| 摘要点击次数: 159 |
| 全文下载次数: 76 |
| 中文摘要: |
| 摘 要：［目的］ 分析2019年甘肃省肿瘤登记地区宫颈癌流行特征及2010—2019年变化趋势。［方法］ 根据国家癌症中心制定的数据质量审核评价标准，整理甘肃省2019年23个肿瘤登记点上报的宫颈癌发病和死亡资料，计算发病（死亡）率、标化发病（死亡）率、不同年龄组及城乡发病（死亡）率、伤残调整寿命年（DALY）等。中国人口标化率使用2000年全国普查标准人口年龄构成计算，世界人口标化率采用Segi世界标准人口年龄构成计算。运用Joinpoint Regression Program（线性回归模型）计算年度变化百分比（APC），分析2010—2019年甘肃省宫颈癌变化趋势。［结果］ 2019年甘肃省肿瘤登记地区宫颈癌发病共报告1 173例，粗发病率为25.78/10万，中标率为18.93/10万，世标率为17.35/10万，0~74岁累积发病率为1.85%，占女性全部恶性肿瘤发病的10.26%；死亡病例数共224例，粗死亡率与中标死亡率分别为4.92/10万和3.18/10万，世标死亡率为3.08/10万，0~74岁累积死亡率为0.37%，占女性全部恶性肿瘤死亡的4.95%。年龄别发病在50~54岁达到高峰，死亡率在70~74岁年龄组达到高峰。地区分布中，中标发病率及死亡率最高的均是庆阳市庆城县。2010—2019年甘肃省宫颈癌中标发病率APC为3.20%（95%CI：-1.07%~7.69%），死亡率呈下降趋势（APC=-8.00%，95%CI：-13.08%~-2.58%），趋势变化具有统计学意义（P<0.05）。DALY率从2010年的1.47/千人年上升至2019年3.10/千人年。［结论］ 2010—2019年甘肃省宫颈癌疾病负担逐渐加重，农村地区发病率高于城市，应积极采取措施减轻宫颈癌的疾病负担。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the epidemiological characteristics of cervical cancer in cancer registration areas of Gansu Province in 2019 and trend from 2010 to 2019. ［Methods］ According to the data quality review and evaluation criteria of the National Cancer Center， the incidence and mortality data of cervical cancer reported from 23 cancer registration areas in Gansu Province in 2019 were collected. The crude incidence and mortality rates， age-standardized incidence and mortality rates (ASIR and ASMR)， age-specific incidence and mortality rates， and disability-adjusted life years (DALY) were calculated. The age-standardized rate was adjusted by Chinese standard population in 2000 (ASIRC， ASMRC) and by world standard population (ASIRW， ASMRW). The Joinpoint linear regression model was used to calculate annual percentage change (APC) and analyze the change trend of cervical cancer in Gansu Province from 2010 to 2019. ［Results］ In 2019， 1 173 cases of cervical cancer were reported in Gansu cancer registration areas， the crude incidence rate was 25.78/105， ASIRC and ASIRW were 18.93/105 and 17.35/105， the cumulative rate (0~74 years old) was 1.85%， accounting for 10.26% of all new female cancer. The number of deaths from cervical cancer was 224， the crude mortality rate was 4.92/105， ASMRC and ASMRW was 3.18/105 and 3.08/105， the cumulative rate (0~74 years old) was 0.37%， accounting for 4.95% of all female cancer deaths. The incidence peaked in age group of 50~54 years old， and mortality peaked in the age group of 70~74 years old. In the regional distribution， Qingcheng County had the highest incidence and mortality rate. The APC of cervical cancer incidence rate in Gansu Province from 2010 to 2019 was 3.20% (95%CI：-1.07%~7.69%)； the APC of mortality rate was -8.00% (95%CI：-13.08%~-2.58%， P<0.05). The DALY rate rose from 1.47 per 1 000 person years in 2010 to 3.10 per 1 000 person years in 2019. ［Conclusion］ From 2010 to 2019， the disease burden of cervical cancer in Gansu Province increased， and the incidence rate in rural areas was higher than that in urban areas. Measures should be taken to reduce the burden of cervical cancer. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |