| 穆慧娟,礼彦侠,马 祥,等.2016—2020年辽宁省肿瘤登记地区恶性肿瘤流行状况及2006—2020年趋势分析[J].中国肿瘤,2025,34(4):279-289. |
| 2016—2020年辽宁省肿瘤登记地区恶性肿瘤流行状况及2006—2020年趋势分析 |
| Cancer Incidence and Mortality in Liaoning Cancer Regi-stration Areas from 2016 to 2020 and Trends from 2006 to 2020 |
| 投稿时间：2024-04-16 |
| DOI：10.11735/j.issn.1004-0242.2025.04.A005 |
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| 中文关键词: 恶性肿瘤 发病率 死亡率 趋势 辽宁 |
| 英文关键词:cancer incidence mortality trend Liaoning |
| 基金项目:辽宁省自然科学基金指导计划（20180550495） |
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| 摘要点击次数: 51 |
| 全文下载次数: 19 |
| 中文摘要: |
| 摘 要：［目的］ 分析辽宁省肿瘤登记地区2016—2020年恶性肿瘤发病和死亡状况及2006—2020年流行趋势。［方法］ 收集2016—2020年辽宁省肿瘤登记地区上报的恶性肿瘤发病与死亡资料，计算发病与死亡粗率、标化率、累积率（0~74岁）和年龄别率等，标化率使用2000年中国人口（简称中标率）和Segi世界标准人口（简称世标率）年龄构成为标准分别进行计算；利用Joinpoint软件对发病、死亡趋势进行分析。 ［结果］ 2016—2020年辽宁省肿瘤登记地区恶性肿瘤粗发病率为422.30/10万，中标率为215.67/10万，世标率为209.52/10万；城市发病中标率（225.00/10万）高于农村（190.15/10万），男性中标发病率（221.47/10万）高于女性（213.03/10万）。2016—2020年恶性肿瘤粗死亡率为254.22/10万，中标率为113.26/10万，世标率为112.91/10万，城市中标死亡率（113.12/10万）与农村（113.01/10万）基本持平，男性中标死亡率（146.86/10万）高于女性（83.46/10万）。肺癌发病（世标率为46.13/10万）和死亡（世标率为32.04/10万）均居辽宁省首位。2006—2020年城市恶性肿瘤粗发病率、中标率和世标率均为升高趋势（AAPC=3.921%，t=16.222，P＜0.05；AAPC=0.823%，t=2.409，P＜0.05；AAPC=0.875%，t=2.933，P＜0.05）；城市女性粗发病率、中标率和世标率均为升高趋势（AAPC=4.151%，t=15.888，P＜0.05；AAPC=1.597%，t=4.819，P＜0.05；AAPC=1.514%，t=4.752，P＜0.05）。同期城市恶性肿瘤粗死亡率呈升高趋势（AAPC=3.175%，t=14.745，P＜0.05），死亡世标率呈下降趋势（AAPC= -0.908%，t=-2.273，P＜0.05）；男、女性死亡率均为升高趋势（AAPC=3.010%，t=6.032，P＜0.05；AAPC=2.820%，t=5.921，P＜0.05），仅女性死亡中标率和世标率（AAPC=-1.487%，t=-2.437，P＜0.05；AAPC=-2.680%，t=-2.246，P＜0.05）的下降趋势有统计学意义。2016—2020年农村恶性肿瘤发病率、中标率和世标率变化趋势均无统计学意义，但男性发病率呈升高趋势（AAPC=2.025%，t=3.853，P＜0.05）。同期农村恶性肿瘤粗死亡率升高（AAPC=3.577%，t=9.377，P＜0.05），死亡中标率和世标率虽呈降低趋势但均无统计学意义，男女性死亡率也均为升高趋势（AAPC=3.377%，t=10.615，P＜0.05；AAPC=3.978%，t=7.245，P＜0.05），死亡中标率和世标率虽呈下降趋势，但均无统计学意义。［结论］ 2016—2020年辽宁地区癌症负担高于中国平均水平，应针对城乡差异，因地制宜地制定肿瘤防控政策和措施。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze cancer incidence and mortality in Liaoning cancer registration areas from 2016 to 2020 and the trends from 2006 to 2020. ［Methods］ Cancer data in cancer registration areas in Liaoning Province from 2016 to 2020 were collected. ?壮he incidence and mortality， age-standardized rate， cumulative rate (0～74 years old)， and age-specific rate were calculated. Age-standardized incidence and mortality rate were calculated by the Chinese standard population(ASIRC，ＡＳＭＲＣ) and Segi world standard population (ASＩRW，ＡＳＭＲＷ). Joinpoint software was applied to analyze the trends of incidence and mortality. ［Results］ From 2016 to 2020， the crude incidence rate of cancer in Liaoning cancer registration areas was 422.30/105， the ASIRC and ASIRW were 215.67/105 and 209.52/105. The ASIRC was higher in urban areas (225.00/105) than that in rural areas (190.15/105)， and higher in male (221.47/105) than that in female (213.03/105). The crude mortality rate was 254.22/105， the ASMRC and ASMRW were 113.26/105 and 112.91/105. The ASMRC in urban areas (113.12/105) was the same as that in rural areas (113.01/105)， and higher in male (146.86/105) than that in female (83.46/105). The ASIRW of lung cancer was 46.13/105， and the ASMRW was 32.04/105， both ranking the first of all cancers. From 2006 to 2020， the crude incidence， ASIRC and ASIRW in urban areas showed an increasing trend(AAPC=3.921%， t=16.222， P<0.05； AAPC=0.823%， t=2.409， P<0.05； AAPC=0.875%， t=2.933， P<0.05). The crude incidence， ASIRC and ASIRW in urban female were all rising (AAPC=4.151%， t=15.888， P<0.05； AAPC=1.597%， t=4.819， P<0.05； AAPC=1.514%， t=4.752， P<0.05). During the same period， the cancer mortality in urban areas showed an increasing trend(AAPC=3.175%， t=14.745， P<0.05)， and the ASMRW showed a decreasing trend(AAPC=-0.908%， t=-2.273， P<0.05). The crude mortality of both men and women showed an increasing trend(AAPC=3.010%， t=6.032， P<0.05； AAPC=2.820%， t=5.921， P<0.05)， while the crude mortality and ASMRW for female showed a significant downward trend(AAPC=-1.487%， t=-2.437， P<0.05； AAPC=-2.680%， t=-2.246， P<0.05). From 2016 to 2020， the crude incidence， ASIRC and ASIRW in rural areas showed no significant change； however， the crude incidence in male was increasing(AAPC=2.025%， t=3.853， P<0.05). In the same period， the crude mortality rate in rural areas increased(AAPC=3.577%， t=9.377， P<0.05)， while there was no significant change in the ASMRC and ASMRW. The crude mortality of both men and women showed an increasing trend (AAPC=3.377%， t=10.615， P<0.05； AAPC=3.978%， t=7.245， P<0.05)， while there was no significant change in ASMRC and ASMRW. ［Conclusion］ The cancer burden in Liaoning from 2016 to 2020 was higher than the average level in China， cancer prevention and control should be further strengthened in the provice. |
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