| 付艳芳,李道娟,刘言玉,等.2012—2020年河北省肿瘤登记地区肺癌流行特征及疾病负担[J].中国肿瘤,2025,34(6):452-463. |
| 2012—2020年河北省肿瘤登记地区肺癌流行特征及疾病负担 |
| Prevalence Characteristics and Disease Burden of Lung Cancer in Hebei Cancer Registration Areas from 2012 to 2020 |
| 投稿时间：2025-01-06 |
| DOI：10.11735/j.issn.1004-0242.2025.06.A005 |
|
 |
| 中文关键词: 肺癌 发病率 死亡率 疾病负担 河北 |
| 英文关键词:lung cancer incidence mortality burden of disease Hebei |
| 基金项目:河北省重点研发计划（22377716D） |
|
| 摘要点击次数: 33 |
| 全文下载次数: 12 |
| 中文摘要: |
| 摘 要：［目的］ 分析2012—2020年河北省肿瘤登记地区肺癌流行特征及疾病负担。［方法］ 收集2012—2020年河北省肿瘤登记处肺癌数据，计算各年份发病（死亡）例数、粗发病（死亡）率、中国人口年龄标化率（中标率）、世界人口年龄标化率（世标率）和年龄别发病（死亡）率等指标。采用2000年中国标准人口构成和Segi世界标准人口构成对数据进行标化。使用Joinpoint模型计算肺癌世标发病率及死亡率的年度变化百分比（annual percentage change，APC）和平均年度变化百分比（average annual percentage change，AAPC），计算伤残调整寿命年（disability-adjusted life years，DALY）、因早死导致的寿命损失年（years of life lost，YLL）和因伤残导致的寿命损失年（years lived with disability，YLD）以及相关率。［结果］ 2012—2020年河北省肿瘤登记地区肺癌世标发病率为33.13/10万，男、女性世标发病率分别为44.56/10万和22.54/10万，城乡世标发病率分别29.05/10万和33.52/10万，年龄别发病率均在80~84岁年龄组达到峰值。2012—2020年肺癌世标发病率呈下降趋势（AAPC=-3.99%，P＜0.001）。2012—2020年肺癌世标死亡率为25.80/10万，男、女性死亡率分别为36.56/10万和15.96/10万，城乡死亡率分别为25.14/10万和26.12/10万，年龄别死亡率在85岁及以上年龄组达到峰值。2012—2020年肺癌世标死亡率呈下降趋势（AAPC=-4.65%，P＜0.001）。 2012—2020年河北省肿瘤登记地区肺癌DALY为484 194人年，其中男性占66.77%，女性占33.23%，城市地区占35.57%，农村地区占64.43%，肺癌DALY率为3.31‰。［结论］ 2012—2020年河北省肿瘤登记地区肺癌发病和死亡率均呈下降趋势，但中老年人发病死亡负担逐渐加重。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the prevalence characteristics and disease burden of lung cancer in Hebei cancer registration areas from 2012 to 2020. ［Methods］ Lung cancer data were collected from the Hebei Provincial Cancer Registry from 2012 to 2020. The crude incidence/mortality rates， age-standardized incidence/mortality rates by Chinese standard population (ASIRC/ASMRC) and by world standard population (ASIRW/ASMRW) were calculated. The Joinpoint model was used to calculate the annual percentage change (APC) and average annual percentage change (AAPC). Years of life lost (YLL) and years lived with disability (YLD) and the disability-adjusted life years (DALY) were calculated. ［Results］ From 2012 to 2020， the ASIRW of lung cancer in Hebei cancer registration areas was 33.13/105， 44.56/105 for men and 22.54/105 for women， respectively； the incidence rates of urban and rural areas were 29.05/105 and 33.52/105, respectively. The incidence rates increased with ages， reaching a peak in the age group of 80~84 years old. There was a decreasing trend in the ASIRW of lung cancer (AAPC=-3.99%， P<0.05). From 2012 to 2020， the ASMRW of lung cancer was 25.80/105， 36.56/105 for men and 15.96/105 for women， respectively； the mortality rates of urban and rural areas were 25.14/105 and 26.12/105， respectively. The mortality rates increase with ages， reaching a peak in the age group of 85 and above years old. There was a decreasing trend in the mortality of lung cancer (AAPC=-4.65%， P<0.001) from 2012 to 2020. The DALY of lung cancer in Hebei Province from 2012 to 2020 was 484 194 person-years， with male accounting for 66.77%， female accounted for 33.23%， the DALY rate of lung cancer was 3.31‰， of which 35.57% in urban areas and 64.43% in rural areas. ［Conclusion］ Lung cancer incidence and mortality rate in Hebei cancer registration areas from 2012 to 2020 showed a decreasing trend. The disease burden is gradually increasing with age in middle-aged and elderly population. |
|
在线阅读
查看全文 查看/发表评论 下载PDF阅读器 |