| 徐 军,陈海珍,陆玲玲,等.前列腺癌医院登记病例478例生存率分析[J].中国肿瘤,2025,34(6):477-483. |
| 前列腺癌医院登记病例478例生存率分析 |
| Survival Analysis of 478 Hospitalized Patients with Prostate Cancer |
| 投稿时间：2024-05-13 |
| DOI：10.11735/j.issn.1004-0242.2025.06.A008 |
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| 中文关键词: 前列腺癌 随访 生存率 肿瘤登记 江苏 |
| 英文关键词:prostate cancer follow-up survival rate cancer registration Jiangsu |
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| 摘要点击次数: 34 |
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| 中文摘要: |
| 摘 要：［目的］ 对2007—2017年南通市肿瘤医院登记住院的前列腺癌病例进行生存率分析。［方法］ 以医院为基础登记收集前列腺癌患者，并结合以人群为基础的肿瘤随访模式进行生存结局的随访，截止日期为2020年12月31日。2007—2017年登记住院的前列腺癌患者共478例，其中476例获得了生存结局信息，随访率达到了99.58%。采用SPSS 25.0进行统计分析，生存数据采用Kaplan-Meier法绘制生存曲线，采用Log-rank检验进行生存率比较。［结果］ 前列腺癌患者入院平均年龄为（71.74±8.02）岁，其中60~79岁年龄组人数最多（79.08%）。患者的中位生存时间为43个月；1、3、5、10年观察生存率分别为77.20%、56.07%、43.01%及24.53%。35~59、60~79、80岁及以上年龄组5年生存率分别为31.73%、46.64%、29.65%，差异有统计学意义（P<0.05）。Ⅰ~Ⅱ期、Ⅲ期、Ⅳ期及分期不明患者的5年生存率分别为88.10%、71.66%、33.35%、37.55%，差异有统计学意义（P<0.001）。2007—2012年和2013—2017年两个时期5年生存率分别为32.85%、47.79%，差异有统计学意义（P<0.05）。辖区内不同地区的生存率也存在统计学差异（P<0.05）。［结论］ 本组以医院为基础的前列腺癌住院患者生存率得到了较大的提升，早期病例可获得较好的生存率，但老年患者的生存率仍面临挑战。应继续加强前列腺癌的综合防控措施，提高患者预后和生活质量。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the survival rate of prostate cancer patients hospitalized in Nantong Tumor Hospital from 2007 to 2017. ［Methods］ A total of 478 prostate cancer patients were admitted in Nantong Tumor Hospital from 2007 to 2017 and 476 cases (99.58%) were followed up till December 31， 2020. The survival rate of patients was analyzed with Kaplan-Meier method； Software SPSS 25.0 and the Log-rank test were employed for statistical analysis. ［Results］ The average age of prostate cancer patients at admission was (71.74±8.02) years old， and 79.08% were aged 60~79 years. The median survival time was 43 months， and the observed 1-， 3-， 5- and 10-year survival rates were 77.20%， 56.07%， 43.01% and 24.53%， respectively. The 5-year survival rates for the age groups of 35~59， 60~79 and ≥80 years old were 31.73%， 46.64% and 29.65%， respectively (P<0.05). The 5-year survival rates for patients with stage Ⅰ~Ⅱ， stage Ⅲ， stage Ⅳ， and unknown stage were 88.10%， 71.66%， 33.35% and 37.55%， respectively (P<0.001). The 5-year survival rates for the periods 2007—2012 and 2013—2017 were 32.85% and 47.79%， respectively (P<0.05). Furthermore survival rates differed significantly across different regions within the jurisdiction (P<0.05). ［Conclusion］ Over the past decade， the survival rate of hospital-based prostate cancer patients has significantly improved. Early-stage cases can achieve better survival rates， but the survival rate of elderly patients remains a challenge. Efforts should be made to reduce the proportion of patients with unknown staging. Comprehensive measures for prostate cancer prevention and control should be strengthened to reduce incidence， improve prognosis and enhance quality of life of patients. |
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