| 再依奴尔·阿不都外力,阿布都沙拉木·依米提,赵 婷.2010—2021年新疆维吾尔自治区12万例恶性肿瘤住院患者生存分析[J].中国肿瘤,2025,34(6):484-490. |
| 2010—2021年新疆维吾尔自治区12万例恶性肿瘤住院患者生存分析 |
| Survival Analysis of 120 Thousand Hospitalized Cancer Patients in Xinjiang Uyghur Autonomous Region from 2010 to 2021 |
| 投稿时间：2024-05-17 |
| DOI：10.11735/j.issn.1004-0242.2025.06.A009 |
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| 中文关键词: 恶性肿瘤 生存率 医院登记 新疆 |
| 英文关键词:cancer survival rate hospital-based registry Xinjiang |
| 基金项目:新疆维吾尔自治区自然科学基金面上项目（2022D01C287） |
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| 中文摘要: |
| 摘 要： ［目的］ 分析2010—2021年新疆维吾尔自治区恶性肿瘤住院患者的生存情况。［方法］ 本调查覆盖了2010年1月1日至2021年12月31日在新疆医科大学附属肿瘤医院确诊及住院治疗的恶性肿瘤患者，共计123 515例。通过回顾患者病历、微信联络、短信和电话跟踪等多种随访手段搜集患者生存数据。随访时间截至2024年4月1日。利用寿命表法，以性别分层计算各病种恶性肿瘤患者1、2、3、5年总生存率（overall survival，OS）。应用Kaplan-Meier法绘制分病种恶性肿瘤患者的总体生存曲线。［结果］ 恶性肿瘤患者1、2、3、5年OS依次为79.4%、70.2%、65.5%和60.3%；男性患者5年OS为42.0%，女性患者则高达71.6%。在众多恶性肿瘤类型中，甲状腺癌患者的5年OS最高，为98.0%，胰腺癌患者5年OS仅为12.3%。与2010—2012年相比较，2019—2021年首次治疗患者5年OS明显提升，不同住院时期患者整体OS之间差异有统计学意义（P＜0.001）。［结论］ 2010—2021年新疆维吾尔自治区绝大部分恶性肿瘤住院患者在接受标准化的医疗诊断和治疗后能取得较好的疗效，女性的生存率明显高于男性。 |
| 英文摘要: |
| Abstract：［Purpose］ To analyze the survival of hospitalized cancer patients in Xinjiang Uyghur Autonomous Region from 2010 to 2021. ［Methods］ A total of 123 515 cancer patients admitted in Affiliated Cancer Hospital of Xinjiang Medical University from January 1， 2010 to December 31， 2021 were included in the analysis. The data were collected from medical records review， telephone visits and death registry， with the last follow-up till April 1， 2024. Life table was applied to evaluate the 1-， 2-， 3- and 5-year overall survival(OS) rate， and the data were stratified by sex， age group and period. Kaplan-Meier method was applied for survival analysis. ［Results］ The 1-， 2-， 3- and 5-year OS of cancer patients were 79.4%， 70.2%， 65.5% and 60.3%. The 5-year OS of men and women were 42.0% and 71.6% respectively. Thyroid cancer held the highest 5-year survival rate (98.0%)， while pancreatic cancer the lowest (12.3%). The 5-year survival rates during 2019—2021 were significantly higher than those during 2010—2012. The difference of overall OS among patients in different hospitalization periods was statistically significant(P<0.001). ［Conclusion］ In Xinjiang Uyghur Autonomous Region most hospitalized cancer patients have relatively good outcomes under standardized diagnosis and treatment from 2010 to 2021. The survival rate of women is higher than that of men. |
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