| Purpose: Analyzing the screening results of upper gastrointestinal tract cancer in the Huai River Basin region of Henan Province from 2013 to 2021.
Method: Since 2013, the Cancer Early Diagnosis and Treatment Program has been implemented in the Huai River Basin region of Henan Province, targeting townships or villages with higher incidence and mortality rates. Employing cluster sampling, residents aged 40 to 69 in the area were screened. Initially, an assessment of high-risk individuals was conducted. Individuals identified as high-risk underwent an "endoscopy + iodine staining" examination, and suspicious lesions were biopsied for pathological diagnosis. Individuals detected with low-grade intraepithelial neoplasia or higher were statistically analyzed for various grades of lesions, positive case detection rates, and early detection rates.
Results: From 2013 to 2021, the detection rate of various-level lesions in the upper gastrointestinal tract in the Huai River Basin region of Henan Province was 4.96% (1980/39895). Among these, the detection rate of precancerous lesions was 4.59% (1831/9895), positive case detection rate was 0.83% (330/39895), early case detection rate was 0.62% (248/39895), with an early diagnosis rate of 75.15%. The detection rates of various-level lesions in males were significantly higher than in females (P<0.05), and with increasing age, there was a trend of increasing detection rates for various-level lesions (P<0.05).
Conclusion: Screening efforts contribute to the timely detection of precancerous lesions and early-stage cancer patients. Additionally, males and the elderly are crucial target populations in upper gastrointestinal tract cancer screening, necessitating increased participation rates for more effective screening outcomes. |
