2023-2024年长沙市结直肠癌筛查成本效果及效益分析
Cost effectiveness and benefit analysis of colorectal cancer screening in Changsha City from 2023 to 2024
投稿时间:2024-09-26  修订日期:2024-11-13
DOI:
中文关键词:  长沙市  结直肠癌  成本效果分析  成本效益分析
英文关键词:Changsha city  Colorectal cancer  Cost-effectiveness analysis  Cost–benefit analysis
基金项目:
作者单位邮编
黄霜 长沙市疾病预防控制中心 410004
徐明忠* 长沙市疾病预防控制中心 410004
胡劲松 长沙市疾病预防控制中心 
黄渊秀 长沙市疾病预防控制中心 
吴梦怡 长沙市疾病预防控制中心 
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中文摘要:
      目的 评价2023-2024年长沙市结直肠癌筛查效果、效益。方法 收集长沙市结直肠癌筛查数据及成本资料,计算问卷高危率、肠镜顺应性、病变检出率,对筛查方案进行成本-效果和成本-效益评价方法评价。结果 长沙市结直肠癌筛查招摹61957人完成问卷调查,高危者17322人,高危率为27.96%;基因检测数14139份,阳性数1133份,基因检测阳性率为8.01%;肠镜检测数为694例,顺应性为61.25%。结肠癌、腺瘤、无蒂/广基锯齿状病变等癌前病变、非腺瘤性息肉检出率分别为1.59%、42.51%、22.48%。本研究筛查总成本为367.10万元,总效益为1285.28万元。成本效益比为1:3.50。不同病变类型筛查的早期发现成本系数(Early detection cost index, EDCI)不同,,范围为0.10~ 2.47,均小于5。结论2023-2024年长沙市结直肠癌筛查具有良好的经济效果和效益,对长沙市结直肠癌的早期发现、早期诊断、早期治疗起到了推动作用。
英文摘要:
      Purpose To evaluate the effectiveness and benefit of colorectal cancer screening in Changsha city from 2023 to 2024. Methods The data and cost data of colorectal cancer screening in Changsha were collected, and the high-risk rate, colonoscopy compliance and lesion detection rate were calculated. The cost-effectiveness and cost-benefit evaluation methods of screening programs were evaluated. Results 61957 people were recruited for colorectal cancer screening in Changsha, and 17322(27.96%) were at high risk,1133(8.01%) were positive for gene detection .The compliance rate was 61.25%. The detection rates of precancerous lesions and non-adenomatous polyps were 1.59% , 42.51% and 22.48% respectively. The total cost of screening in this study was 3.671 million yuan, and the total benefit was 12.8528 million yuan. The cost-benefit ratio was 1:3.50. The Early Detection Cost Index (EDCI) for screening different types of lesions varies, ranging from 0.10 to 2.47, all of which were less than 5. Conclusion The colorectal cance screening in Changsha city from 2023 to 2024 has good efficacy and benefit. and has played a promoting role in the early detection, diagnosis, and treatment of colorectal cancer in Changsha
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