2008-2020年连云港市结直肠癌发病趋势及年龄变化
Incidence trend and change in the age distribution of Colorectal cancer in Lianyungang from 2008 to 2020
投稿时间:2024-12-27  修订日期:2025-03-31
DOI:
中文关键词:  结直肠癌  年龄  趋势
英文关键词:Colorectal cancer  Age  Trend
基金项目:
作者单位邮编
马昭君 连云港市疾病预防控制中心 222000
董建梅 连云港市疾病预防控制中心 222000
柴莉莉 连云港市疾病预防控制中心 222000
秦绪成 连云港市疾病预防控制中心 222000
张伟伟 连云港市疾病预防控制中心 222000
相璐 连云港市疾病预防控制中心 222000
仲玮 连云港市疾病预防控制中心 222000
王威 连云港市疾病预防控制中心 222000
李伟伟* 连云港市疾病预防控制中心 222000
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中文摘要:
      目的 分析2008-2020年连云港市结直肠癌发病趋势及年龄变化。方法 收集整理2008-2020年覆盖连云港市所有县区结直肠癌数据资料,质控后计算结直肠癌各年份发病率、中国人口标化发病率(中标率)、平均发病年龄、标化平均发病年龄和标化年龄发病构成比等指标。应用Joinpoint回归模型分析(标化)发病率的平均年度变化百分比(AAPC),使用线性回归模型计算(标化)平均发病年龄与年份之间的相关性,计算并比较其2008年和2020年标化年龄发病构成比变化。结果 2008-2020年连云港市结直肠癌中标发病率呈明显上升趋势,AAPC为3.68%(P<0.05)。全市结直肠癌的标化平均发病年龄由2008年62.22岁增长至2020年的63.03岁,年均增长β=0.132岁(P=0.013)。各年龄组发病率趋势中,50岁以下各组无增长趋势,50~59岁组开始出现增长趋势,60岁及以上各组均呈现明显增长趋势,在60~69岁组发病率增长幅度最大。结论 2008-2020年连云港市结直肠癌发病水平呈现明显上升趋势,尤其是50岁及以上年龄组人群。针对目前流行情况,建议采用适宜的多重防控措施,降低结直肠癌疾病负担。
英文摘要:
      Objective To investigate trend of incidence and mean age for colorectal cancer(CRC) in Lianyungang from 2008 to 2020. Methods Collected and qualitied control the data of all cancer registries in Lianyungang City from 2008 to 2020, and calculated the CRC’s crude incidence rate, the standardized incidence rate by Chinese population, crude and adjusted mean age, and standardized age-specific incidence composition. The Joinpoint regression model and the linear regression model were used respectively to analyze the average annual percentage change (AAPC)and the correlation between the (standardized) average age of onset and the year. The standardized age-specific incidence composition were calculated and compared between 2008 and 2020. Results The standardized incidence of CRC in Lianyungang showed upward trends, AAPC was 3.68(P<0.05). The standardized mean age at onset increased from 62.22 in 2008 to 63.03 in 2020,average annual growth β= 0.132(P=0.013). In all age groups, there was no obvious increase in the age group below 50 years old, the age group between 50 and 59 years old began to show an increasing trend. All age groups above 60 years old showed an obvious increasing trend, while the age group between 60 and 69 years old increased the fastest. Conclusions From 2008 to 2020 in Lianyungang, the standardized rates of incidence were on the rise, especially above 50 years old. Adopting appropriate multiple prevention and control measures to reduce the burden of CRC in response to the current epidemic situation.
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