| 曾庆鹏,赵 峻.基于国际新分类肺腺癌亚型的临床研究进展[J].肿瘤学杂志,2019,25(5):387-393. |
| 基于国际新分类肺腺癌亚型的临床研究进展 |
| Progress on Clinical Research of Lung Adenocarcinoma Subtypes Based on New International New Classification |
| 投稿时间：2018-03-27 |
| DOI：10.11735/j.issn.1671-170X.2019.05.B001 |
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| 中文关键词: 肺腺癌 IASLC/ATS/ERS分类 分子分型 个体化治疗 |
| 英文关键词:lung adenocarcinoma IASLC/ATS/ERS classification molecular subtype individualized treatment |
| 基金项目: |
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| 中文摘要: |
| 摘 要：1999年和2004年世界卫生组织（WHO）/国际肺癌研究协会（IASLC）肺癌组织学分类将大多数腺癌归于混合亚型，在指导临床方面存在局限性。同时，随着分子病理及靶向治疗研究的进展，过去的肺腺癌分类已无法适应目前的发展。2011年IASLC、美国胸科学会（American Thoracic Society，ATS）及欧洲呼吸学会（European Respiratory Society，ERS）联合多学科发表了关于肺腺癌国际多学科新分类。新分类实施以来，有关肺腺癌组织学亚型及临床特征、生存预后及分子生物学等的研究取得一定成果，为指导临床决策及研究开展提供了新的方向和目标。 |
| 英文摘要: |
| Abstract：According to World Health Organization(WHO)/Association for the Study of Lung Cancer(IASLC) classification of lung cancer in 1999 and 2004，most adenocarcinomas were classified as mixed subtypes，which limited its role in clinical guidance. Meanwhile，with the development of molecular pathology and targeted therapy，the traditional classification of lung adenocarcinoma can not adapt to the current development. Therefore，a new classification of lung adenocarcinoma was published by an international multidisciplinary committee sponsored by IASLC，American Thoracic Society(ATS) and European Respiratory Society(ERS) in 2011. Since the implementation of the new classification，achievements have been made in the study of histological subtypes，clinical features，prognosis and molecular biology of lung adenocarcinoma，which provides new direction and target for guiding clinical decision-making and research. |
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